Symptomatic Tx and Complications of Cancer Flashcards

1
Q

When should you increase a pts LA opioid?

A

When BTP is used 4 or more times daily

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2
Q

Starting opioid therapy regimen

A

Start on short acting for a few days
Calc 24 hr usage and convert to LA
Keep 10% short acting for BTP
Increase dose if BTP used 4+ times

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3
Q

Increasing an opioid dose

A

Add total daily dose (BTP+LA)

Keep 10% short acting for BTP

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4
Q

Decreasing opioid dose

A

Taper by less than or =25%

to prevent withdrawal

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5
Q

Changing opioid drugs

A

Convert equal dose and
decrease by 25% b/c
incomplete cross tolerance

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6
Q

All opioid conversions are based on

A

Morphine

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7
Q

10mg IV morphine is equal to…

A

2 IV hydromorphone
8 PO hydromorphone
AND
30 mg PO morphine, oxy, hydro

***Minus 25%

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8
Q

Conversions for morphine to methadone

A

If 1000 or less
Morphine 10 = 1 methadone
Minus 25%

If over 1000
Morphine 20 = 1 methadone
Minus 25%

Methadone is PO ONLY!
Long acting

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9
Q

Convert morphine to fentanyl

A

50-75 PO morphine
= 25 mcg/hr fentanyl

Then decrease by 25%

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10
Q

Opioids to avoid/use caution with in renal failure

A
Take Cover MOM
Tramadol
Codeine
Meperidine
Oxycodone
Morphine
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11
Q

High risk emetogenic IV chemo drugs

A
AC Combo 
(doxorubicin or epirubicin + cyclophos)
Cisplatin 50+
Cyclophos 1500+
Doxo 60+
Epirubicin 90+
Ifosfamide 10+
  -all mg/m2
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12
Q

Mod Risk emetogenic IV chemo drugs

A
Carboplatin
Cisplatin below 50
Cyclops below 1500
Doxo below 60
Epirubicin below 90
Ifosfamide below 10
MTX 250+
Oxaliplatin
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13
Q

Low Risk emetogenic IV chemo drugs

A
Cabazetaxel
Docetaxel
Eribulin
Etoposide
5-FU
Gemcitabine
Ixa
MTX 50-250
Mitox
Paclitaxel
Pemetrexed
Topotecan
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14
Q

Tx for high risk IV emetogenic chemo drugs

A
Day 1 (3 drugs)
 -setron (SSRI)
 -dexamethasone (CCS)
 -aprepitant (NK-1)
Day 2-4 (2 drugs)
 Dexa+aprepitant
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15
Q

Tx for mod risk IV emetogenic chemo drugs

A
Day 1 (2 drugs)
 -setron (SSRI)
 -dexamethasone (CCS)
Day 2-3 (1 drug)
 either of the two above
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16
Q

Tx for low risk IV emetogenic chemo drugs

A
(One day only)
Choose one from:
 -dexamethasone
 -metoclopramide
 -prochlorperazine
17
Q

Mod-High risk emetogenic PO chemo drugs

A

Cyclophos 100+
Estramustine
Etoposide
Temozolomide 75+

18
Q

Tx for Mod-High risk PO emetogenic chemo drugs

A

PO granisetron or ondansetron