Systemic Eye Disease Flashcards Preview

Opthamology COPY > Systemic Eye Disease > Flashcards

Flashcards in Systemic Eye Disease Deck (17)
Loading flashcards...
1
Q

What is the pathogenesis of diabetic retinopathy?

A
Chronic hyperglycaemia=
Glycosylation of protein/basement membrane=
loss of pericytes=
microaneurysm=
leakage + ischaemia
2
Q

What are signs of non proliferative retinopathy?

A
microaneurysms / dot + blot haemorrhages
hard exudate
cotton wool patches
abnormalities of venous calibre
Intra-retinal microvascular abnormailities
3
Q

Where may new vessels grow if ischaemia is severe?

A

iris

4
Q

What do diabetic patients lose vision from?

A

retinal oedema affecting the fovea
vitreous haemorrhage
scarring/ tractional retinal detachment

5
Q

What is the management for diabetic retinopathy?

A

Laser (PRP, Macular grid)
Surgery – vitrectomy
Rehabilitation (blind/partial sighted)

6
Q

Can young people have extensive retinopathy?

A

Yes

7
Q

List the features of hypetensive retinopathy.

A
Attenuated blood vessels-copper or silver wiring
cotton wool spots
hard exudates
retinal haemorrhage
optic disc oedema
8
Q

What happens in accelerated hypertension?

A

very dramatic fundal appearance

can have decreased vision

9
Q

When might you see the retinal nerve fibre layer becoming swollen except at fovea (cherry red spot)?

A

central retinal artery occlusion

10
Q

What is HLA-B27 related to and what does it cause?

A

ankylosing spondlytis

uveitis

11
Q

What cause of eye disease may cause jaw claudication?

A

giant cell artitis

12
Q

What is the most common cause of both unilateral and bilateral proptosis?

A

thyroid disease

13
Q

What is thyroid eye disease characterised by?

A

swelling of the extraocular muscles and orbital fat

14
Q

What can SLE cause in eye?

A

ocular inflammation

15
Q

What eye disease may rheumatoid arthritis cause?

A

Dry eyes (Keratoconjunctivitis Sicca)
Scleritis
Corneal melt

16
Q

What can Sjogrens cause infiltration of?

A

Dry eyes (Keratoconjunctivitis Sicca)
Scleritis
Corneal melt

17
Q

What eye disease may Steven-Jonson syndrome cause?

A

Symblepharon
occlusion of lacrimal glands
corneal ulcers