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Flashcards in Systems Path I - Neuro PPT 2 Deck (56)
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1

inflammatory response and the majority of the organisms reside in the CSF

leptomeningitis

2

parenchymal infection that is usually bacterial or fungal

cerebritis

3

parenchymal infection, but the term usually refers to viral infections with necrosis, perivascular lymphocytic cuffing and microglial nodules

encephalitis

4

have many polymorph nuclear leukocytes within a necrotic core surrounded by granulation tissue

abscesses

5

what does TORCH stand for

infection of a a developing fetus or newborn
T - toxoplasmosis
O - other agents
R - rubella (measles)
C - cytomegalovirus
H - herpes simplex

6

most common source of meningitis

hematogenous - from abscess, heart valve, lung infection

7

bacterial meningitis causes

polymorpho nuclear responses

8

viral meningitis causes

lymphocytic responses

9

fungi and mycobacterial meningitis causes

granulomatous reactions

10

meningitis that peak incidence is in children (6 months to 5 years) caused by H influenzae

bacterial

11

acute pyogenic meningitis is usually _____ and infiltrates in the walls off arteries and veins

bacterial

12

CSF findings in meningitis

high neutrophils
decreased glucose
increased protein

13

what is the most common bacterial organism causing neonatal meningitis

e coli, group B streptococci

14

chronic basilar meningitis may block CSF flow through the foramina of Magendie and Luschka, leading to hydrocephalus, headache, nausea and vomiting

tuberculous meningitis

15

most common disease of the CNS (mostly of children and young adults)

viral meningitis (lymphocytic or aseptic meningitis)

16

inflammation of gray matter of the spinal cord, due to infection by poliovirus

poliomyelitis

17

transmitted to human via saliva by bite, results in difficulty swallowing and a tendency to aspirate fluids that leads to hydrophobia

rabies

18

encephalitis localizes mainly in one or both temporal lobes which become swollen and hemorrhagic and necrotic

herpes virus

19

childhood chicken pox

herpes zoster

20

reactivated herpes zoster

shingles

21

chronic, lethal, viral infection of the brain caused by measles virus; mainly in childhood

sub-acute sclerosing-pan-encephalitis

22

virus responsible for progressive multifocal leukoecencephalopathy

JC virus (john cunningham virus)

23

seen in patients with associated immune suppression or chronic disease (lymphoma, AIDS); presence of giant bizarre astrocytes and oligodendrocyte nuclear inclusion

progressive multifocal leukoencephalopathy

24

rapidly progressive ataxia and dementia, finding of spongiform encephalopathy, included in CJD, long incubation period

prion disease

25

patient 50-70 yo, severe dementia, early stage CJD, personality changes, and impaired judgment

prions disease

26

meningo vascular inflammation leading to pachy meningitis and strokes caused by obliterative endarteritis

neurosyphilis

27

neurosyphilis: infiltration of meninges and vessels by lymphocytes and plasma cells leading to thickening of meninges

meningovasculitis

28

neurosyphilis: atrophy, loss of cortical neurons in frontal lobes, proliferation of microglial cells

general paresis

29

neurosyphilis: inflammation lesions involving meninges and vessels in subarachnoid space of dorsal nerve roots

tabes dorsalis (posterior column degneration)

30

seizures occur in roughly 50% of cases

intracerebral abscesses