Table 2 - Antihypertensives Flashcards Preview

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Flashcards in Table 2 - Antihypertensives Deck (30)
1

Renin-angiotensin inhibitors: ACEI

Captopril, Lisinopril, Fosinopril

2

NaCl symporter inhibition in the DCT increasing Na and Cl excretion max 5% of filtered NaCl

HCTZ, Chlorthalidone

3

Alpha-1 Blockers

Prazosin

4

Vasodilators: Direct acting

Hydralazine

5

Diuretics: "Thiazide-Like"

Chlorthalidone

6

Direct acting arteriolar vasodilator

Hydralazine

7

Angiotensin Receptor blockers: ARBs

Losartan

7

Direct renin inhibitor

Aliskirin

9

B1, B2, A1 blockers

Carvedilol

11

Vasodilators: DHP CCB

Amlodipine, Nifedipine

12

Direct adjunct: K+ Sparing

Triamterine

13

Loop diuretic

Furosemide, Turosemide, Edecrin

14

Adrenergic **B1 and B2** receptor inhibitor, reduction in myocardial oxygen demand

Propranolol (NON SELECTIVE B-BLOCKER)

15

Vasodilators: NDHP CCB

Cardizem, Verapamil

16

**Selective** B1 adrenergic receptor inhibitor

Metoprolol tartrate/succinate, Atenolol

17

Selective alpha-1 blocker which relaxes smooth muscle in arteries, veins, and the prostate

Prazosin

18

Centrally acting A2 adrenergic agonist

Clonidine, Methyldopa

19

Mixed **alpha and beta** receptor inhibition

Carvedilol

20

SURPRISE Which beta blocker can be used in heart failure?

Carvedilol

21

Direct inhibitor of Na+ influx in DCT and CCT

Triamterene

22

Inhibits Na+-K+-2Cl- symporter in TAL of loop and distal tubule

Furosemide

23

Stimulates alpha 2 receptors in the brain stem which stimulates an inhibitory neuron resulting in reduced sympathetic outflow from CNS which results in a reduction in TPR

Clonidine

24

Central alpha-adrenergic inhibition decreases sympathetic outflow to heart, kidneys, and peripheral vasculature

Methyldopa

25

Selectively and competitively blocks AT 1 (1000X greater) and AT 2 receptors

Losartan

26

Direct renin inhibitor preventing conversion of antiotensinogen to angiotensin I (AT1) which reduces conversion to angiotensin II (AT2) producing arteriolar vasodilation

Aliskirin

29

Dilate coronary arteries and decrease myocardial oxygen demans

Cardizem, verapamil

30

Sympatholytics: Peripheral Adrenergic "R" Blockers - Beta blockers

Propranolol, Metoprolol Tartrate/Succinate, Atenolol

30

Diuretics: Thiazides

Hydrochlorathiazide

30

Competitive inhibitor of ACE preventing conversion angiotensin I to angiotensin II decreasing vasoconstriction by angiotensin II and decreases aldosterone secretion

Captopril, Lisinopril, Fosinopril

30

Vasodilation due to blocking calcium channels in vascular smooth muscle and myocardium

Amlodipine, Nifedipine