Test 3 Part 2 Flashcards Preview

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Flashcards in Test 3 Part 2 Deck (33)
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1
Q

Obesity can decrease fertility in women, but what about men?

A

obesity may decrease testosterone and other hormones leading to low sperm count

2
Q

Many women with PCOS show signs of insulin resistance and/or obesity. What is PCOS?

A

Polycystic Ovarian Syndrome is a common condition in young women

3
Q

T/F: Primary infertility occurs when a patient has conceived in the past, but is now unable to.

A

False; this is secondary infertility. Primary occurs when the patient has never conceived

4
Q

What types of problems make up the majority of female infertility?

A

ovulatory dysfunction and tubal/peritoneal factors

5
Q

How often is infertility due to male factors?

A

25%

6
Q

How often is infertility unexplained?

A

20%

7
Q

What is a Mullerian duct abnormality?

A

cervical (female) factor which may cause infertility

8
Q

For psychological aspects affecting infertility, put these in order:
Anger, Grief, Denial, Resolution

A

Denial
Anger
Grief
Resolution

DAGR

9
Q

When performing semen analysis, how long should the patient abstain prior to the test? How long do you have to get the sample to the lab?

A

2-5 days;

within 1 hour

10
Q

T/F: Postcoital tests, Antibody studies, and Sperm Penetration Assay are all test for evaluating female factors associated with fertility.

A

False; male factors

11
Q

T/F: Ovulatory factors make up 20% of female factor infertility.

A

False; 40%

12
Q

T/F: Luteal phase defect evaluation is the gold standard for evaluating female fertility.

A

False; this is a controversial evaluation

13
Q

To evaluate fertility, when is ovarian reserve typically evaluated?

A

when patient is over 35 years of age

14
Q

T/F: Transvaginal Ultrasounds, Hysterosalpingogram and Laparoscopy with chronotubation are all used to evaluate the pelvic factors associated with female fertility.

A

True

15
Q

T/F: Pelvic exams are only used to evaluate pelvic factors of fertility.

A

False; also cervical factor

16
Q

What does ART stand for?

A

Assisted Reproductive Technologies

17
Q

What is the term for the removal of eggs from the ovary, fertilizing them in the laboratory, and replacing them in the patients uterus?

A

In Vitro Fertilization

18
Q

When was the first live In Vitro Fertilization?

A

June 1978

19
Q

T/F: In Vitro Fertilization success rates have improved from 6.6% in 1985 to nearly 30% as of 2003.

A

True

20
Q

When evaluating risks for In Vitro Fertilization, what is the most imorotant prognostic indicator?

A

the age of the female partner (if over 43 y/o the live brith rate is only 2.4%)

21
Q

What was the original reason for the development of In Vitro Fertilization?

A

patients with tubal disease

22
Q

Superovulation, Oocyte retrieval, Fertilization with capacitate spermn/intracytoplasmic sperm injection, embro culture, embryo transfer, and luteal phase support are all different techniques for what?

A

IVF (In Vitro Fertilization)

23
Q

What is the term for stimulating the production of several eggs to improve success of egg aspiration?

A

superovulation

24
Q

Clomiphene citrate, Human menopausal gonadotropins, FSH products, and LH agonists are all used (often in combination) for what purpose?

A

ovulation induction therapy

25
Q

How many follicles should be developing before proceeding with egg aspiration?

A

at least 2 or 3

26
Q

What are the 2 methods used for oocyte retrieval?

A

laparoscopy (rare today) and Ultrasound-guided transvaginal aspiration

27
Q

Which is a less expensive method of oocyte retrieval, laparoscopy or Ultrasound-guided transvaginal aspiration?

A

US is cheaper and can be done on an outpatient basis

28
Q

T/F: During fertilization with capacitated sperm, once the sperm has undergone the physcial changes needed to penetrate and fertilize an egg the sperm has a considerably long incubation period in a culture medium.

A

False; short incubation period

29
Q

During fertilization with capacitated sperm, why is important not to mix the sperm and eggs too early?

A

if mixed too early, fertilization and cleavage will not take place

30
Q

When is intracytoplasmic sperm injection used?

A

in cases of male factor infertility and in cases where preimplantation genetic diagnosis (PGD) is performed

31
Q

How long are embryos incubated before being replaced in the patient’s uterus for IVF?

A

3-5 days

32
Q

Typically, how many embryos are implanted during IVF for patients under 35? 35-37? 38-40? over 40?

A

under 35 -> 2
35-37 -> 2-3
38-40 -> 3-4
over 40 -> 5

33
Q

When might only 1 embryo be implanted during IVF?

A

If the patient is under 35 and has already had a successful IVF cycle