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Flashcards in Therapeutics Deck (32)
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1
Q
Semisolid emulsion of oil in water
Contain emulsifier & preservative
High water content
Cool & moisturise
Non greasy
Easy to apply
Cosmetically				acceptable
A

Cream

2
Q
Semisolid grease/oil (soft paraffin)
No preservative
Occlusive and emollient
Restrict transepidermalwater loss
Greasy - lesscosmetically 					attractive
A

Ointment

3
Q

Liquid formulation
Suspension or solution of medication in water, alcohol or other liquids
If contain alcohol, may sting
Treat scalp, hair-bearing areas

A

Lotion

4
Q

Thickened aqueous lotions
Semi-solids, containing high molecular weight polymers eg methylcellulose
Treat scalp, hair bearing areas, face

A

Gels

5
Q
Semisolids
Contain finely powdered material eg ZNO
Stiff, greasy,difficult to apply
Protective,occlusive,hydrating
Often used in cooling, drying, soothing bandages
A

Paste

6
Q

How much emollient should you prescribe?

A

250-500g weekly

7
Q

How much does a non-proprietary emollient cost?

A

£3 per 500g
(e.g. soft paraffin, emulsifying ointment, aqueous cream)

Non-proprietary cost £5-12

8
Q

Corticosteroid mode of action?

A

Vasoconstrictive
Anti-inflammatory
Anti-proliferative

9
Q

Mild steroid

A

Hydrocortisone

10
Q

Moderate steroid

A

Clobetasone butyrate

Modrasone

11
Q

Potent steroid

A

Betamethasone valerate

12
Q

Very potent steroid?

A

Clobetasol propionate

13
Q

Medication you could use in lichen planus?

A

Steroid

14
Q

How much ointment do you need to cover whole body?

A

20-30g

15
Q

Side effects of topical steroids

A

Steroid rosacea
Perioral dermatitis
Fixed telangiectasia

16
Q

rinse/soak/bath use in acute exudative eczema, pompholyx

A

Potassium permanganate

17
Q

Abx for acne? (CET)

A

Clindamycin
Erythromycin
Tetracycline

18
Q

Abx for rosacea?

A

Metronidazole

19
Q

Abx for impetigo?

A

Mupirocin

Fusidic acid

20
Q

Treatment for pityriasis versicolour?

A

Anti-yeast

21
Q

What are keratolytics used for?

A

Used to soften keratin:

  • viral warts
  • hyperkeratotic eczema and psoriasis
  • corns and calluses
  • to remove keratin plaques in scalp
22
Q

Example of a keratolytic?

A

Salicylic acid 10-40%

23
Q

Treatment of warts?

A
Mechanical paring plus
Keratolytics  e.g.Salicylic acid
Formaldehyde
Glutaraldehyde
Silver nitrate
Cryotherapy (usually                            liquid nitrogen)
Podophyllin (genital warts)
24
Q

Podophylin

A

Used for genital warts

25
Q

Menthol
Capsaicin
Camphor/phenol
Crotamiton

A

Anti-pruritis

camphor/phenol for pruritis ani

26
Q

Topical psoriasis treatments?

A
Coal tar
Vitamin D analogue
Keratolytic
Topical steroid
Dithranol
27
Q

Side effects of dithranol?

A

Irritant and stains normal skin

vitamin D can be irritant

28
Q

When could you use imiquimod?

A

Solar keratoses
Lentigo maligna
Bowen’s disease
Verrucae

29
Q

Why might you use tacrolimus in children?

A

Avoids some of the side effects of steroids

30
Q

Treatment for chronic plaque psoriasis?

A

Coal tar
Vitamin D analogues
Dithranol

31
Q

Treatment for scalp psoriasis

A

Greasy ointments to soften scale
Tar shampoo
Steroids in alcohol base
Vitamin D analogue

32
Q

Treatment for psoriasis in axilla?

A

Topical steroid for face, flexure and groin/genitals