Tissues 5 Flashcards

1
Q

How much of a person is water?

A

60%

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2
Q

How much of the water content is intracellular?

A

55%

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3
Q

How much of the water content is extracellular?

A

45%

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4
Q

Describe the composition of body water.

A

Interstitial fluid - 36%
Blood plasma - 7%
Transcellular fluid - 2% (eg CSF)

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5
Q

Where is more Na found?

A

Extracellularly

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6
Q

Where is more K found?

A

Intracellularly

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7
Q

Where is more Ca found?

A

Extracellularly

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8
Q

Where is more Cl found?

A

Extracellularly

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9
Q

Whats the difference between plasma and interstitial fluid?

A

Plasma has more protein

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10
Q

Where are more protein anions found?

A

Intracellularly

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11
Q

Why is intracellular pH lower?

A

H+ conc is greater there.

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12
Q

Osmolarity of all cells is same outside as inside. Why?

A

To prevent osmotic damage

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13
Q

What is osmolarity?

A

Measure of all solute particles in a solution

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14
Q

Why isn’t osmolarity a good guide of the effects of cell volume?

A

Doesn’t depend on cell permeability

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15
Q

What is tonicity?

A

Defines strength of a solution as it affects final cell volume

Depends on both membrane permeability and solution composition

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16
Q

Hypertonic?

A

Outside impermeant solutes greater than intracellular solutes.

Cell shrinks

17
Q

Hypotonic?

A

Intracellular impermeant solutes greater than extracellular

Cell swells

18
Q

Isotonic?

A

Osmolarity of impermeant solutes equal either side of the membrane.

Cell remains the same

19
Q

In reality, why do cells not burst?

A

Presence of Na/K pump on all cell membranes.

Maintains Na conc lower inside the cell than outside

20
Q

When tissue fluid is released, where do lipid soluble molecules diffuse out of?

A

The endothelium of the capillaries.

21
Q

What do pores in the capillary wall allow?

A

Exchange of water and water soluble molecules.

22
Q

Name 3 causes of oedema

A

Inflammation, trauma, hypertension