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Flashcards in Toxic gases 2 Deck (13)
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1
Q

what gas poisoning is also known as “Silo filler’s disease”?

A

Nitrogen oxide

2
Q

what color is nitrogen dioxide?

A

reddish brown (NO2) - major pollutant

mixture of NO2 and N2O4 = yellow brown

3
Q

Where does NO2 often settle?

A

it’s heavier then air - forms layers on top of silage and settles down the chute

4
Q

What does NO2 in water form?

A

Nitric acid and nitric oxide

NO2 has a low water solubility

5
Q

at what levels does Nitrogen oxide cause moderate irritation of the eyes and upper respiratory mucosa?

A

50 - 150 ppm

6
Q

What is more toxic - acute exposure to high concentrations of NO2 or chronic exposure to low concentrations of NO2?

A

Acute high concentrations

7
Q

What is the MOA of nitrogen oxide gases?

A

Direct irritation to MM by forming nitric acid
Damage to the lungs (bronchi/alveoli)

death is from hypoxia

8
Q

What lesions can be seen with NO2 poisoning?

A

Pulm edema, hemorrhage, emphysema and inflammation of the bronchioles, cyanosis, methemoglobinemia

*methemoglobin is a form of hemoglobin where ferric (Re+3) iron has a lower binding affinity for O2 than ferrous (Fe+2) iron

9
Q

What is the prognosis in animals with NO2 poisoning?

A

Low in acute high concentration exposures

better in animals chronically exposed to lower concentrations

10
Q

Sulfur dioxide and sulfur trioxide are what type of pollutants?

A

Industrial

come from fossil fuel combustion at power plants primarily and from other industrial facilities

11
Q

what is formed when sulfur oxide gases come into contact with moist mm?

A

Sulfuric acid - irritant

the odors can also cause coughing, choking, and suffocation

12
Q

What are the ranges of toxic dose of SO2 for cats, herbivores, and pigs?

A

Cats - SO2 at 500ppm for 30 mins = fatal

Grazing animals - SO2 at 500ppm for 1 hour = dangerous

Pigs - SO2 at 5-40 ppm for 8 days = poisoning

13
Q

What is the MOA of SO2 poisoning?

A

Direct irritation of the mm and reflex bronchoconstriction
Lung damage
Death due to hypoxia