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Flashcards in Tumour Markers Deck (43)
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1
Q

What is alpha feta protein relevant to

A

Germ cell/testicular cancers

Hepatocellular cancers

2
Q

What is alpha feta protein used for

A

Diagnosis
Monitoring treatment
Detecting reoccurrence

3
Q

What other cancers can AFP be associated with

A

Colorectal
Gastric
Hepatobilary
Lung

4
Q

What benign conditions can AFP be associated with

A

Cirrhosis
Pregnancy
Neural tube defects

5
Q

Which marker is used for hepatocellular, germ cell and testicular cancers

A

Alpha feta protein

6
Q

What cancer is calcitonin a tumour marker for

A

Medullary thyroid cancer

Calcitonin produced in the c cells of the thyroid

7
Q

What is calcitonin used for

A

Diagnosis, monitoring treatment, detecting reoccurrence

8
Q

What other associated cancers is calcitonin associated with

A

None known

9
Q

What associated benign conditions are associated with calcitonin

A

C cell hyperplasia

10
Q

What marker is used in medullary thyroid cancer

A

Calcitonin

11
Q

What tumour marker CA125 used in

A

Ovarian cancer

12
Q

What is the CA125 used for in ovarian cancer

A

Monitoring ovarian cancer

Prognosis after chemotherapy

13
Q

What other associated cancers to CA125 are there

A
Breast
Cervical
Endometrial 
Hepatocellular 
Lung
Non-Hodgkins lymphoma
Pancreatic
Medullary thyroid 
Peritoneal
Uterine
14
Q

What associated benign conditions are there with tumour marker CA125

A
Liver disease
Cystic fibrosis
Pancreatitis
Urinary retention
Diabetes
Heart failure
Pregnancy 
SLE
sarcoid
RA
Diverticulitis 
IBS
Endometriosis
Fibroids
15
Q

What tumour marker is associated with ovarian cancer

A

CA125

16
Q

What cancer is CA19-9 associated with

A

Pancreatic cancer

17
Q

What can tumour marker CA19-9 be used for

A

Monitoring pancreatic cancer

18
Q

What other cancers can be associated with Ca19-9

A
Colorectal 
Gastric 
Hepatocellular 
Oesophageal 
Ovarian
19
Q

What associated benign conditions are there to tumour marker CA19-9

A
Acute cholangitis
Cholestasis
Pancreatitis
Diabetes
IBS
Jaundice
20
Q

What is CA15-3 associated with

A

Breast cancer

21
Q

What is CA15-3 used for

A

Monitoring breast cancer

22
Q

What other cancers can tumour marker CA 15-3 be associated with

A

Hepatocellular

Pancreatic

23
Q

What associated benign conditions are associated with CA15-3

A

Cirrhosis
Benign breast disease
Normal health

24
Q

What is the tumour marker associated with breast cancer

A

CA 15-3

25
Q

What is carcinoembryonic antigen associated with

A

Colorectal cancer

26
Q

What can CEA be used for

A

Monitoring adenocarcinima

27
Q

What other cancers are associated with CEA

A
Breast 
Lung
Gastric 
Mesothelioma 
Oesophageal 
Pancreatic
28
Q

What associated benign conditions are associated with CEA

A
Smoking 
Chronic liver disease
Chronic kidney disease
Diverticulitis 
Jaundice
29
Q

What tumour marker is associated with colorectal cancer

A

CEA carcinoembryonic antigen

30
Q

What is human chorionic gonadotropin (hCG) associated with

A

Germ cell/testicular

Gestational trophoblastic

31
Q

What can hCG be used for

A

Diagnosis
Prognosis
Monitoring treatment of germ cell tumours

32
Q

What other cancers are associated with hCG

A

Lung

33
Q

What other associated benign conditions are associated with hCG

A

Pregnancy

34
Q

What tumour marker is hCG associated with

A

Germ cell tumour
Testicular
Gestational trophoblastic

35
Q

What cancer are paraprotein associated with

A

Myeloma

36
Q

What can the tumour marker paraprotein be used for

A

Diagnosis
Monitoring treatment
Detecting reoccurrence

37
Q

What other cancers are associated with paraprotein

A

None known

38
Q

What benign conditions are associated with paraprotein

A

None known

39
Q

What tumour marker is myeloma associated with

A

Paraprotein

40
Q

What tumour is thyroglobulin a tumour marker for

A

Thyroid
Follicular
Papillary

41
Q

What can thyroglobulin be used for

A

Monitoring treatment

Detecting reoccurrence

42
Q

What other cancers are associated with thyroglobulin

A

None known

43
Q

What benign conditions are associated with thyroglobulin

A

None known