Vasoregulation Flashcards Preview

Pharma mt2 > Vasoregulation > Flashcards

Flashcards in Vasoregulation Deck (6)
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1
Q

Name some vasoregulating drugs:

A

Nitroglycerin,
Alpha1 antagonist: prazosine, doxasozine
Hydralazin

2
Q

What’s the mechanism of nitroglycerin?

A

Ca2+ channel blockers

3
Q

What’s the mechanism of hydralazin

A

PDE- inhibitors

RAA system blockers

4
Q

Pharmacological effects of vasoregulators:

A
  • Arterial vasodilation peripherial resistance, afterload decreases
  • Venodilation CVP decreases preload will decrease
  • Water excretion preload will decrease
  • Does not alter contractility BUT heart performance increases!! + decrease blood pressure.
5
Q

Indications og vasoregulating drugs

A
  • Heart failure
  • Hypertension
  • Proteinuria
6
Q

Side effects of vasoregulating drugs:

A
  • Azotaemia
  • Hypotension tiredness, faintness
  • GI-disturbances: anorexia, vomiting, diarrhea