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Flashcards in week 9 Deck (20)
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1
Q

cerebellum function

A

regulates/ coordinates UMNs that control voluntary movement, tone, posture

2
Q

cerebellum needs 2 pieces of information

A
  1. UMNs tell cerebellum INTENTION
  2. Proprioceptive tracts tell cerebellum where limbs and trunk are (POSITION); Vestibular system tells cerebellum where head is
3
Q

cerebellar cortex is composed of what 3 uniform and consistent layers

A

molecular layer
purkinje layer
granular layer

4
Q

molecular layer is what layer

A

sparse, outermost layer

5
Q

function of molecular layer

A

primarily an exchange area for incoming information (UMN and proprioceptive)

6
Q

purkinje layer is what layer

A

intermediate layer; huge single cell layer (purkinje cells)

only efferent neurons of the cortex (only neurons that leave the cortex)

7
Q

function of purkinje cell layer

A

all are inhibitory

8
Q

granular layer is what layer

A

inner-most layer; numerous tiny cells

9
Q

deep cerebellar nuclei location

A

deep in medulla of cerebellum

10
Q

how many deep cerebellar nuclei are there

A

3 pair (6 total)

11
Q

deep cerebellar nuclei function

A

excitatory (tonically active) to UMN centers; axons leave cerebellum and synapse on all umn cneters in brain

12
Q

what cells are inhibitory to the deep cerebellar nuclei

A

purkinje cells

13
Q

cerebellum is affected by viruses during what trimesters

A

first trimester cellular migration and last trimester cellular migration

14
Q

first trimester cellular migration

A

cells migrate from metencephalon into cerebellar cortex; destined to become purkinje and dep nuclei

15
Q

last trimester cellular migration

A

cells migrate to form granular layer

16
Q

what are the clinical signs of cerebellar disease

A
symmetrical ataxia
no paresis or parlaysis
hypermetria
head and neck tremors
absent menace response
postural responses may be delayed
no single loss of function
dysmetria
17
Q

congenital cerebellar disease

A

present at birth; usually non-progressive (viral in utero or developmental genetic)

18
Q

abiotrphy cerebellar disease

A

cells die early due to genetic defect in cellular metabolism (ok at birth, early onset, progressive)

19
Q

congenital disease common in

A

cats (panleukopenia virus) and cattle (BVD virus)

20
Q

abiotrophy common in

A

dogs (kerry blue and jack russel); horse (arabian and arabian cross)