Wk 5 Bone Flashcards Preview

Derm > Wk 5 Bone > Flashcards

Flashcards in Wk 5 Bone Deck (44)
Loading flashcards...
1
Q

Endocrine function of osteoblasts

A

stimulation of PTH receptors causes release of osteoclast stimulating factor

–> bone resorption

2
Q

In what manner does bone grow

A

appositional growth

3
Q

Osteoblasts form what type of layer on bone

A

epitheloid layer

4
Q

What are the recesses that house osteocytes called

A

lacunae

5
Q

Are bones:
vascularized?
innervated?

A

yes

yes, especially periosteum

6
Q

Cellular origins of osteoclasts

A

monocytes

7
Q

Special microscopic characteristic of osteoclasts

A

multinucleated

8
Q

Howship’s lacunae

A

depression where osteoclast is located

9
Q

Hydroxyapatite crystals

A

calcium storage in bone

10
Q

What type of crystals store calcium in bone

A

hydroxyapetite

11
Q

What type of collagen is found in bone

A

type I

12
Q

Glycoproteins in bone matrix function to what

A

bind different matrix components together

13
Q

Cancellous/medullary bone

A

interior of bone, web-like network

14
Q

Where does most bone turnover happen

A

medullary bone (more surface area)

15
Q

Compact/cortical bone

A

dense, hard

16
Q

Woven bone

A

“primary bone”

present up to 4 y/o and healing

17
Q

Lamellar bone

A

“secondary bone”
replaces woven bone
mature bone

18
Q

Diaphysis

A

area between epiphyseal plates

19
Q

Metaphysis

A

transition from diaphysis to epiphysis

20
Q

Epiphysis

A

distal end/head of bone

21
Q

Epiphyseal plate

A

growth plate

22
Q

Covering of epiphyseal plate

A

perichondrium

23
Q

Where is periosteum found

A

only on diaphysis

24
Q

What type of bone is found in the metaphysis

A

medullary

25
Q

What type of cartilage is on the articular surfaces of bone

A

hyaline

26
Q

What type of cartilage makes up epiphyseal plate in children

A

haline

27
Q

What direction does bone mature

A

distal –> proximal

28
Q

Sharpey’s fibers

A

anchor periosteum to bone

29
Q

Where is the endosteum found

A

between marrow and matrix

30
Q

What direction does the Halversian system run

A

longitudinally

31
Q

What direction do the Volkmann’s Canals run

A

radially

32
Q

What are interstitially lamellae

A

remnants of partially resorbed bone

33
Q

What bones develop via intramembranous ossification

A

skull, mandible, maxilla, clavicle

34
Q

What is the stem cell percursor for intramembranous ossification

A

embryonic

35
Q

What bones develop via endochondral ossification

A

most

36
Q

Where are primary and secondary ossification centers

A

primary: center of diaphysis
secondary: in epiphysis

37
Q

3 phases of fracture repair

A
  1. hemorrhage
  2. soft callus
  3. hard callus
38
Q

2 types of cells found in synovial capsule

A

fibroblasts

macrophages

39
Q

What types of cells secrete synovial fluid

A

fibroblasts

40
Q

Adult marrow color

A

yellow (may convert back to red when it needs to be)

41
Q

Scurvy

A

ascorbate deficiency

42
Q

Osteomalacia

A

prolonged adult deficiency of vitamin D

43
Q

Rickets

A

vitamin D deficiency during childhood, can lead to bowed legs as a result of not being able to bear weight

44
Q

Osteoporosis

A

osteoclast activity > osteoblast activity