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Saskia Chapman
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Decks in this class (40)
Trigger 6: Lung structure
Which structure is responsible fo...,
Surface area of lung 2,
How are alveoli adapted to be eff...
21
cards
Trigger 6: IPF
Incidence of ipf 1,
Idiopathic pulmonary fibrosis is 2,
Pulmonary fibrosis is the 3
45
cards
Trigger 6: Wound Healing
Tissue repair definition 1,
Parenchymal cells 2,
Connective tissue is 3
40
cards
Trigger 6: IPF management and treatment
Management pathway for ipf patien...,
Successful management is dependen...,
Monitoring test 3
26
cards
Trigger 6: Mechanism of IPF
Causes and risk factors of ipf 1,
Mutations 2,
Sftpc gene 3
15
cards
Trigger 6: Viral involvement in IPF
Incidence of acute exacerbation i...,
Some patients have slow disease p...,
Increasing evidence to show that ...
38
cards
Trigger 6: Animal models
How can animal models be used to ...,
What is the ideal ipf model 2,
What is the ideal ipf model for d...
25
cards
Trigger 7: TBI
Definition of tbi 1,
Tbi is not a result of 2,
How many deaths result from tbi 3
48
cards
Trigger 7: TBI associated disorders
Chronic traumatic encephalopathy 1,
Is there a cure for cte 2,
Cte 3
27
cards
Trigger 7: TBI and cells of the brain
Name the glial cells of the cns 1,
Name the glial cells of the pns 2,
Two types of glia 3
51
cards
Trigger 7: polarization state of microglia in TBI
M1 and m2 1,
Patrolling microglia ramified 2,
What trigger the activation of an...
28
cards
Trigger 7: Microglia
Tbi results in neuroinflammation ...,
Which substances leak out of the ...,
Swelling and inflammation from ti...
33
cards
Trigger 7: Diagnosis and treatment of TBI
Name 6 diagnosis imaging for tbi 1,
Worst form of diagnostic imaging ...,
Ct 3
36
cards
Trigger 7: Animal models
Cervical dislocation occurs due to 1,
Types of injury that can be model...,
Penetrating focal injury 3
24
cards
Trigger 9: Developmental disorders
Definition of dd 1,
How many rare diseases 2,
How many rare diseases are genetic 3
42
cards
Trigger 9: Genomic technologies
Which is the oldest genomic techn...,
Which is the newest genomic techn...,
Name 6 forms of genomic technology 3
56
cards
Trigger 9: Genome sequencing
Outline first generation sanger s...,
Outline second next generation se...,
Third generation sequencing produ...
20
cards
Trigger 9: DDs examples
Schizophrenia has a lifetime prev...,
Schizophrenia is heritable 2,
Thought to be caused by high burd...
42
cards
Trigger 9: Phenotypes and genetic variants
Children with dd 1,
Dds can be syndromic 2,
Dds can also be 3
34
cards
Trigger 9: Deciphering Developmental Disorder study
Objective of ddd study 1,
Ddd study is a 2,
Ddd strategy 3
45
cards
Trigger 9: Major classes of genetic variants
Single nucleotide variants relate...,
Insertion deletion indels 2,
Copy number variation 3
20
cards
Trigger 9: questions
Which variant change the number o...,
Why are variants rare 2,
Why are common variants common 3
13
cards
Mutations
Name the two main types of mutati...,
Point mutations are 2,
Frameshift mutations are 3
15
cards
DNA, genes and chromosomes
How many pairs of chromosomes in ...,
How many chromosomes in humans 2,
Autosomal chromosomes 3
15
cards
Genetic testing
Two main types of genetic testing 1,
Molecular testing 2,
What does molecular testing use 3
58
cards
Trigger 10: Obesity Genetics
Bmi 1,
Centiles by age and sex are defin...,
Why should doctors be worried abo...
45
cards
Trigger 10: Genetics and obesity diseases
The human genome is made up of ho...,
How many types of letters 2,
Variation is caused by the differ...
55
cards
Trigger 10: Prader-Willi syndrome
Phenotypes associated with prader...,
How common is prader willi 2,
Prader willi is caused by a defec...
23
cards
Trigger 10: Mendelian randomisation
Mendelian randomisation use 1,
Mendelian randomisation simple 2,
Epidemiologists are interesting i...
23
cards
Trigger 10: ILOs
Neonates with overweight mothers 1,
Maternal traits hypothesised to i...,
Maternal traits hypothesised to d...
48
cards
Genomic sequencing
Genomic sequencing can be used in 1,
History of genetic sequencing can...,
The first generation included the...
19
cards
Trigger 6- IPF summary
Which people are the most prone t...,
Which mutated gene can be a risk ...,
Sftp is a gene which encode 3
18
cards
Trigger 8: Basic epigenetics
Define what the epigenome is 1,
Dna determines 2,
Epigenetic determines 3
57
cards
Trigger 8: Structure of nucleosomes
Role of dna methylation 1,
Dna methylation occurs at 2,
Dna methylation silences genes by 3
31
cards
Trigger 8: Histone modification
Chromatin compaction 1,
Dna is only transcribed and expre...,
When the gene is switched on 3
34
cards
Trigger 8: Non-coding RNA
A non coding rna ncrna 1,
How much of transcriptional outpu...,
Ncrna is probs not 3
22
cards
Trigger 9: Epigenetics in action
During gametogenesis 1,
When genes evade reprogramming 2,
Uniparental disomy 3
44
cards
Trigger 8: Environmental impact on epigenetic profile
Genome can acquire lose methyl gr...,
Dynamic natur eo epigenome provid...,
When is the epigenome particularl...
24
cards
Trigger 8: Epigenetics and cancers
Epigenetic drven gene inactivatio...,
Understanding how genetic and epi...,
Mutations in the epigenetic write...
41
cards
Trigger 8: Interrogating the epigenome
Name a way of interrogating dna m...,
Sodium bisulphiite conversion 2,
Name a sodium bisulphite kit 3
11
cards
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(6-10) Translational Medical Science
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