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Saskia Chapman
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Decks in this class (40)
Trigger 6: Lung structure
Which structure is responsible fo...,
Surface area of lung,
How are alveoli adapted to be eff...
21
cards
Trigger 6: IPF
Incidence of ipf,
Idiopathic pulmonary fibrosis is,
Pulmonary fibrosis is the
45
cards
Trigger 6: Wound Healing
Tissue repair definition,
Parenchymal cells,
Connective tissue is
40
cards
Trigger 6: IPF management and treatment
Management pathway for ipf patients,
Successful management is dependen...,
Monitoring test
26
cards
Trigger 6: Mechanism of IPF
Causes and risk factors of ipf,
Mutations,
Sftpc gene
15
cards
Trigger 6: Viral involvement in IPF
Incidence of acute exacerbation i...,
Some patients have slow disease p...,
Increasing evidence to show that ...
38
cards
Trigger 6: Animal models
How can animal models be used to ...,
What is the ideal ipf model,
What is the ideal ipf model for d...
25
cards
Trigger 7: TBI
Definition of tbi,
Tbi is not a result of,
How many deaths result from tbi
48
cards
Trigger 7: TBI associated disorders
Chronic traumatic encephalopathy,
Is there a cure for cte,
Cte
27
cards
Trigger 7: TBI and cells of the brain
Name the glial cells of the cns,
Name the glial cells of the pns,
Two types of glia
51
cards
Trigger 7: polarization state of microglia in TBI
M1 and m2,
Patrolling microglia ramified,
What trigger the activation of an...
28
cards
Trigger 7: Microglia
Tbi results in neuroinflammation ...,
Which substances leak out of the ...,
Swelling and inflammation from ti...
33
cards
Trigger 7: Diagnosis and treatment of TBI
Name 6 diagnosis imaging for tbi,
Worst form of diagnostic imaging ...,
Ct
36
cards
Trigger 7: Animal models
Cervical dislocation occurs due to,
Types of injury that can be modelled,
Penetrating focal injury
24
cards
Trigger 9: Developmental disorders
Definition of dd,
How many rare diseases,
How many rare diseases are genetic
42
cards
Trigger 9: Genomic technologies
Which is the oldest genomic techn...,
Which is the newest genomic techn...,
Name 6 forms of genomic technology
56
cards
Trigger 9: Genome sequencing
Outline first generation sanger s...,
Outline second next generation se...,
Third generation sequencing produces
20
cards
Trigger 9: DDs examples
Schizophrenia has a lifetime prev...,
Schizophrenia is heritable,
Thought to be caused by high burd...
42
cards
Trigger 9: Phenotypes and genetic variants
Children with dd,
Dds can be syndromic,
Dds can also be
34
cards
Trigger 9: Deciphering Developmental Disorder study
Objective of ddd study,
Ddd study is a,
Ddd strategy
45
cards
Trigger 9: Major classes of genetic variants
Single nucleotide variants relate...,
Insertion deletion indels,
Copy number variation
20
cards
Trigger 9: questions
Which variant change the number o...,
Why are variants rare,
Why are common variants common
13
cards
Mutations
Name the two main types of mutations,
Point mutations are,
Frameshift mutations are
15
cards
DNA, genes and chromosomes
How many pairs of chromosomes in ...,
How many chromosomes in humans,
Autosomal chromosomes
15
cards
Genetic testing
Two main types of genetic testing,
Molecular testing,
What does molecular testing use
58
cards
Trigger 10: Obesity Genetics
Bmi,
Centiles by age and sex are defin...,
Why should doctors be worried abo...
45
cards
Trigger 10: Genetics and obesity diseases
The human genome is made up of ho...,
How many types of letters,
Variation is caused by the differ...
55
cards
Trigger 10: Prader-Willi syndrome
Phenotypes associated with prader...,
How common is prader willi,
Prader willi is caused by a defec...
23
cards
Trigger 10: Mendelian randomisation
Mendelian randomisation use,
Mendelian randomisation simple,
Epidemiologists are interesting i...
23
cards
Trigger 10: ILOs
Neonates with overweight mothers,
Maternal traits hypothesised to i...,
Maternal traits hypothesised to d...
48
cards
Genomic sequencing
Genomic sequencing can be used in,
History of genetic sequencing can...,
The first generation included the...
19
cards
Trigger 6- IPF summary
Which people are the most prone t...,
Which mutated gene can be a risk ...,
Sftp is a gene which encode
18
cards
Trigger 8: Basic epigenetics
Define what the epigenome is,
Dna determines,
Epigenetic determines
57
cards
Trigger 8: Structure of nucleosomes
Role of dna methylation,
Dna methylation occurs at,
Dna methylation silences genes by
31
cards
Trigger 8: Histone modification
Chromatin compaction,
Dna is only transcribed and expre...,
When the gene is switched on
34
cards
Trigger 8: Non-coding RNA
A non coding rna ncrna,
How much of transcriptional outpu...,
Ncrna is probs not
22
cards
Trigger 9: Epigenetics in action
During gametogenesis,
When genes evade reprogramming,
Uniparental disomy
44
cards
Trigger 8: Environmental impact on epigenetic profile
Genome can acquire lose methyl group,
Dynamic natur eo epigenome provid...,
When is the epigenome particularl...
24
cards
Trigger 8: Epigenetics and cancers
Epigenetic drven gene inactivatio...,
Understanding how genetic and epi...,
Mutations in the epigenetic write...
41
cards
Trigger 8: Interrogating the epigenome
Name a way of interrogating dna m...,
Sodium bisulphiite conversion,
Name a sodium bisulphite kit
11
cards
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(6-10) Translational Medical Science
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