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Decks in this class (14)
tumour immunology and immunotherapy of cancer
role of the immune system: summarise evidence for the importance of tumour surveillance by the immune system, and explain how immune responses to tumours have some similarities with those to virus infected cells
40
cards
tumour immunology and immunotherapy of cancer
tumour antigens: explain the concept of tumour-associated antigens giving named examples, and explain how they differ from tumour-specific antigens
12
cards
tumour immunology and immunotherapy of cancer
immunotherapy: summarise approaches being used and developed for tumour immunotherapy, including antibody-based therapy, tumour vaccination and immune checkpoint blockade
20
cards
transplantation
organs: explain which organs can be transplanted, why, and where the transplanted organs come from
40
cards
transplantation
ethical issues: summarise the ethical and structural/organisational issues surrounding organ transplantation
11
cards
transplantation
graft rejection: summarise the immunological issues in transplantation and their impact on organ allocation and rejection after transplantation (including the main types of graft rejection)
38
cards
transplantation
complications: explain the risks and complications associated with transplantation and transplant immunosuppression
13
cards
hypersensitivity, allergy and inflammation
immunological mechanisms: summarise the mechanisms by which IgE, antibodies, immune complexes and T cells can cause tissue damage and inflammation (the four types of hypersensitivity); clinical disease: list examples of the clinical syndromes associated with each type of hypersensitivity reaction
33
cards
hypersensitivity, allergy and inflammation
allergy: summarise the factors underlying the development of atopic/allergic diseases, listing the important clinical features of asthma, hay fever, allergic eczema and anaphylaxis
42
cards
hypersensitivity, allergy and inflammation
patient management: explain the approaches to investigation and management of patients with allergic disorders
14
cards
tolerance and autoimmunity
tolerance: explain the concept of immunological tolerance, and the mechanisms that underlie such tolerance
28
cards
tolerance and autoimmunity
autoimmune disease: explain how defects in tolerance lead to autoimmune diseases, and list factors that may lead to breakdown of self-tolerance
18
cards
tolerance and autoimmunity
clinical disease: list examples of important autoimmune diseases, and outline their immunological mechanisms
8
cards
hypersensitivity, allergy and inflammation
inflammatory dermatoses: summarise the biology and significant clinical manifestations of specific inflammatory dermatoses including acne, eczema, psoriasis, bullous pemphigoid and pemphigus vulgaris
57
cards
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Y2 MCD Immunology
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