A&P Test 1 Flashcards

1
Q

Anatomy

A

The scientific investigation of human structure and form

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2
Q

Physiology

A

The scientific investigation of the function of living things

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3
Q

Hooke

A

discovered cells by looking at cork

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4
Q

Hippocrates (130 BC)

A

first to question that it wasn’t up to the gods or the stars, everything happens for a reason, began searching for answers.

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5
Q

Galen (130 AD)

A

Roman physician of the gladiators, began perfuming dissections on other animals and writing manuals about what he saw. no challengers until 1500

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6
Q

Vesalius (1500)

A

began doing dissection on humans, had to do them quickly because of no way to preserve body. Found that Galen’s manuals had some flaws because of difference between humans and monkeys. Some opposed vesalius and wanted to stick with Galen but he wrote manuals of his own and is known as the Father of Modern Anatomy

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7
Q

Homeostasis

A

the bodies ability to return to internal stability, coined by Walter Cannon.

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8
Q

Negative Feedback Loop

A

if body has over worked it becomes hot so stops working to cool down, then gets cold and works again to get hot. Body is constantly changing, e.g. heart rate. Speeds up when we run, slows down when we sleep but maintains its way around the average.

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9
Q

Positive Feedback Loop

A

body continues to change in the same direction. e.g. birth control, baby pushes on vagina and makes it contract due to hormone release, this pushes baby out some, which releases more hormones and pushes the baby out more.

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10
Q

3 factors of negative feedback loop

A

receptor - sense the change and signals it
integrator - control center
effector - takes directions from integrator and takes action to fix the problem.

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11
Q

hydroxyl

A

(OH) found in sugars and alcohols

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12
Q

methyl

A

(CH2) fats, oils, steroids, amino acids

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13
Q

carboxyl

A

(COOH) amino acids, sugars, proteins

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14
Q

Amino

A

(NH2) amino acids and proteins

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15
Q

Phosphate

A

(H2PO4)

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16
Q

Carbohydrates

A

CH2O is general formula, -sacchar is name, ends in -ose.
Polysaccharide is a long chain of glucose (monosaccharides) Cellulose and starch are two common carbs only difference is humans use starch because its easier to break down than cellulose (less bonds). Glucose is the most common, easiest for our bodies to use.

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17
Q

3 monosaccharides

A

glucose, galatose, fructose (we can’t use fructose so we break it down into glucose.

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18
Q

3 disaccharides

A

Sucrose (glucose + fructose), Lactose (glucose + galactose), Maltose (glucose + glucose)

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19
Q

Conjugated Carbohydrate

A

essential to driving cellular function, glycolipids, glycoproteins, proteoglycans.

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20
Q

glycolipids

A

more lipid than glucose, used in forming the cell membrane

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21
Q

glycoproteins

A

more protein than glucose, forms the mucus that flows through our respiratory and digestive tracts and helps cleanse them

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22
Q

Proteoglycans

A

gelatinous tissues, lubricating joints, and cell adhesion

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23
Q

glycocalyx

A

carbs of the membrane like glycolipids and glycoproteins, function is to help the immune system recognize normal cells from diseased cells or foreign bodies or transplanted cells. It helps with cell adhesion, cushioning, protection

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24
Q

glycogen

A

carb used for storing energy, when we eat we take in glucose, too much glucose for us to use so we store it in glycogen. Glycogen is produced in the liver and then stored in the liver and muscle cells. If we run out of run to store glycogen we turn it into triglycerides and store it in fat cells.

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25
Q

6 types of lipids

A

fatty acids, glycerides, phospholipids, steroids, eioconsanoids, lipid soluble vitamins

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26
Q

fatty acids

A

4-24 carbon and hydrogen molecules with a carboxyl end at one group and a methyl group at the other end. amount of carbon atoms determines function

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27
Q

saturated

A

has all of the hydrogen molecules that it can hold

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28
Q

unsaturated

A

has room for more hydrogen molecules, double bonded carbon somewhere in the chain

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29
Q

glycerides

A

fatty acids bonded to a glycerol. Triglycerides are most common type, glycerol gives an (OH) and fatty acid gives an (H), called dehydration bond. Form of energy storage and insulation (Fat cells)

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30
Q

phospholipids

A

fatty acid tails (hydrophobic), phosphate heads (hydrophilic), and attached to a function group. associated with the cell membrane

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31
Q

eicosanoids

A

chemical communicators of the cell.

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32
Q

leukotrienes

A

stimulate inflammation of the cells, results of allergies. Things get in that shouldn’t and the cells swell up. Allergy medicine stops the signal and cause the cell to reduce in swelling

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33
Q

prostaglandins

A

send chemical signal of pain to the brain. If you take meds the meds are stopping the signal, not addressing the problem.

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34
Q

steroids

A

cholesterols required for proper nervous system function. We make 85% of all of steroids, take in the other 15%, and reuse them, secreted and absorbed from small intestine.

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35
Q

proteins

A

polymers of amino acids (Monomers) with a carboxyl group at one end and an amino group at the other, also have a R group that determines function.

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36
Q

integrated proteins

A

proteins that reach through the entire membrane, help solutes flow through membrane.

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37
Q

peptides

A

2 or more amino acids grouped together by “peptide bond”. dipeptide = 2, tripeptide = 3, 15 or more = polypeptide, 100 more = protein.

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38
Q

protein structure

A
primary = chain of amino acids
scondary = alpha helix or beta pleated
tertiary = both alpha and beta, bonded through Rgroups.
quaternary = two separate chains of polypeptides working together.
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39
Q

nonpolar

A

hydrophobic

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40
Q

polar

A

hydrophilic

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41
Q

amphilic

A

both non polar and polar combined

42
Q

protein functions

A

structure/support, communications, movement and transport, catalysis, recognition/protection, cell adhesion

43
Q

amino acids

A

20 total, R group signifies the function of the amino acid.

peptide bonds hold them together, very strong.

44
Q

enzymes

A

proteins that help with cell reactions, they bond to substrates at an activation site. The purpose is to change the conformation of the substrate to reduce the activation energy. Less energy needed for reaction to occur but get same products. affected by pH and Temp

45
Q

protein conformation

A

the 3D shape of a protein, very dynamic, always changing to help function. helps flow in and out.

46
Q

protein denaturization

A

change in the conformation of the protein which affects the proteins function. changing with pH and Temp, e.g. cooking an egg.

47
Q

protein denaturization

A

change in the conformation of the protein which affects the proteins function. changing with pH and Temp, e.g. cooking an egg.

48
Q

effect of temp and pH on proteins

A

bell curve, if too hot or cold it ill not work as well, if too acidic or basic it will not work as well.

49
Q

nucleic acids

A

found in DNA and RNA, made up of millions of nucleotides and ATP. DNA contains the codes for protein synthesis, sexual reproduction, and cell division.

50
Q

nucleotides

A

contain nitrogenous bases, sugars, and at least 1 phosphate group. ATP has 3 phosphate groups and releases energy by cleaving off one of its own phosphates.

51
Q

nitrogenous bases

A

adenine, cytosine, guanine, thymine, and uracil (RNA only)

52
Q

Cell Theory

A

everything is made up of cells, which are the smallest living things; all cells come from pre-existing cells.

53
Q

Schwann

A

botanist - all plants are made up of cells

54
Q

Schleiden

A

zoologist - all animals are also made up of cells

55
Q

Virchow

A

all cells come from pre-existing cells

56
Q

microvilli

A

finger like projections that increase surface area to help with absorption

57
Q

cilia

A

hairlike projections that help move mucus out of our respiratory and digestive tracts

58
Q

cystic fibrosous

A

chloride pumps fail to make enough saline to layer our tracts Without the saline the mucus gets stuck on cilia and clogs up our tracts. This makes breathing difficult and opens our body up for infections.

59
Q

plasma membrane

A

outer lipid bi-layer of the cell, responsible for cell shape and what travels into and out of the cell.

60
Q

flagella

A

help cells move, sperm are the only human cells with flagella

61
Q

cytoplasm

A

everything inside of the cell but outside of the nucleus, includes organelles and cytosol

62
Q

cytosol

A

fluid of the cytoplasm, where many of the chemical reactions occur.

63
Q

rough ER

A

has ribosomes attached to them for protein synthesis, also makes phospholipids for the cell membrane

64
Q

smooth ER

A

no ribosomes at all, lipid synthesis and detoxification

65
Q

golgi complex

A

modifies and packages proteins that are produced by RER, also synthesizes carbs. Packages proteins and carbs into vesicles and moves them around the cell for secretion or storage.

66
Q

vesicles

A

packages products for secretion or storage, moves the proteins or carbs from the golgi to where they are supposed to go.

67
Q

lysosomes

A

contain enzymes from digesting biological material. Helps breaks part of the cells down, old cells or dead cells.

68
Q

peroxisomes

A

contains enzymes for detoxification, also helps digest materials leftover from metabolism of cells.

69
Q

mitochondria

A

power house of the cell, responsible for producing ATP and providing energy to the cell for reactions

70
Q

centrioles

A

manufactures microtubules for cytoskeleton, basal bodies, cilia, and flagella

71
Q

cytoskeleton

A

protein filaments that are responsible for cell shape, structure, organizing organelles, and moving organelles

72
Q

nucleus

A

brain of the cell, contains all of the DNA to tell the cell what to do

73
Q

nuclear membrane

A

bilayer that controls what comes in and goes out of the nucleus

74
Q

nuclear pores

A

protein rings that are integral, reach through both sides of the membrane to allow things to come in and go out.

75
Q

nucleolus

A

produces ribosomes

76
Q

chromatin

A

loosely packed DNA floating around the nucleus.

77
Q

cytoskeleton

A

contains microfilaments, microtubules, and intermediate filaments

78
Q

microfilaments

A

actin forms a network on the cytoplasm side of the membrane, helps with supporting microvili, phospholipids, cell movement and with myosin causes muscle contractions

79
Q

microtubules

A

bundle of 13 parallel strands called protofilaments, hold everything in place and help with organelle movment

80
Q

intermediate filaments

A

holds the skin together, reduces stress on the cells

81
Q

Membrane trasnport

A

active and passive, passive is down conc. gradient from high to low. active is up gradient and requires energy from the cell to occur.

82
Q

filtration

A

(kidneys) movement of articles through selectively permeable membrane due to hydrostatic pressure

83
Q

facilitated diffusion

A

movement of particles down the conc gradient through a protein that changes its shape to allow movement, no energy is needed.

84
Q

active transport

A

solute binds to the carrier at the receptor site. ATP is needed to change the shape of the carrier so it can fit through the protein and enter the cell. ATP is needed to change the shape of the protein and so the solute can move up the conc gradient from low to high.

85
Q

uniporter

A

carries 1 solute into the cell

86
Q

symporter

A

carries 2 solutes into the cell

87
Q

antiporter

A

carriers 2 or more solutes into the cell but in different directions

88
Q

receptor mediated cytosis

A

only specific chemicals can bind to the receptor sites, once all of the receptor sites are full then the chemicals are packed into a vesicle and brought into the cell.

89
Q

transcytosis

A

uses receptor mediated cytosine to move things into the cell and exocytosis to move them out of the cell at the same time.

90
Q

endocytosis

A

3 types: phaygocytosis, pinocytosis, and recpetor mediated cytosis

91
Q

phaygocytosis

A

bringing solids into the cell through vesicles called phyagosomes

92
Q

pinocytosis

A

cell takes in extra cellular fluid by vesicles and releases it into the cell

93
Q

exocytosis

A

when things need to leave the cell, a secretion vesicle packages it up and carries to the membrane where it fuses with the membranes and then opens up to secret.

94
Q

nuclear anatomy

A

brain of the cell, surround by nuclear envelope, bilayer that acts the same as plasma membrane, controls what comes in and goes out. nuclear pores, protein rings that help move things in and out by changing their shape. Chromatin is the DNA that is floating around the nucleus, histones are proteins that the DNA wraps around.

95
Q

DNA

A

double stranded helix of a nitrogenous base, a sugar, and a phosphate. Has all of the codes for protein synthesis throughout the cell. Gives all of the commands for cellular functions

96
Q

RNA

A

smaller than DNA, needed for DNA replication so the cells can divide, three types, mRNA, rRNA, and tRNA

97
Q

mRNA

A

messenger RNA, function is to take the replicated DNA cell out of the nucleus so it can be copied

98
Q

rRNA

A

function is to read the strand of mRNA and figure out what nitrogenous bases are needed as well as what amino acids are needed to create the new protein

99
Q

tRNA

A

transfer RNA that bring the amino acid to rRNA and attaches it to form the peptide

100
Q

Mitosis

A

cell replication to take the place of dead or used up cells, constantly happening, 4 stages: prophase, metaphase, anaphase, and telophase

101
Q

prophase

A

DNA has condensed into chromosomes and replicated into chromatids, spindle fibers begin to form.

102
Q

metaphase

A

chromatids begin to line up in the center of the cell, spindle fibers run from the centrioles to the centromeres of chromatids.