Articles (Oleic Acid, CLA, Nutragenomics, Pro/Prebiotics, microbiome) Flashcards

1
Q

reduced risk of coronary HD

A

oleic acid

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2
Q

best source of oleic acid

A

olive oil

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3
Q

what might benefit digestive diseases by lowering gastric acid secretion?

A

oleic acid

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4
Q

What can moderate the postprandial hyperactivity of B-cells?

A

oleic acid

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5
Q

What is responsible for the hypotensive effects of olive oil?

A

oleic acid

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6
Q

pimary isomer of CLA from beef

A

cis-9, trans-11

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7
Q

main interest involving CLA

A

obesity

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8
Q

What supp increases palmitoyl transferase-l and uncoupling protein 3 in skeletal m.?

A

CLA

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9
Q

what might be an anti-breast caner component of milk?

A

CLA

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10
Q

CLA’s benefit to bone health involves interaction with what?

A

calcium

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11
Q

What can improve antibody production following hep B vaccination?

A

CLA supp

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12
Q

one potential adverse effect of CLA?

A

increased oxidative markers

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13
Q

hemochromatosis gene

A

HFE

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14
Q

5-methyltetrahydrofolate

A

MTHFR

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15
Q

MTHFR TT genotype

A

NTD’s

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16
Q

MTHFR AA genotype

A

higher angiotensinogen and HTN

- more responsive to DASH diet

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17
Q

different responses to meds according to genotype

A

pharmacogenetics

18
Q

affects genetic performance most

A

malnutrition in 1st and last trimester

19
Q

what can compensate for dysfunctional/absent genes

A

some nutrients, such as folic acid

20
Q

what accounts for 95% of caffeine metabolism?

A

cytochrome P450 1A2 (CYP1A2) in the liver

21
Q

what initiates the breakdown of homocysteine?

A

methylene hydrofolate reductase (MTHFR)

22
Q

do nutrigenetic tests diagnose disease?

A

NO

23
Q

“forgotten organ”

A

microbiome

24
Q

microbiome synthesizes what vitamines?

A

K and B

25
Q

Bile acid signaling through farnesoid X receptor (FXR) results in?

A
  • reduction of triglycerides, cholesterol, and fatty acids

- improvement of glucose metabolism and hepatoprotection

26
Q

BA signaling to TGR-5

A

immune modulatioin and energy metabolism

27
Q

3 bacterial communities

A

Bacterioides, prevotella, or ruminococcus

28
Q

bacterioides-dominated

A

diet high in fat

29
Q

provetella-dominated

A

diet high in carbs

30
Q

ruminococcus-dominated

A

mucins

31
Q

gut dysbiosis and impaired microbiota enzyme activity is seen in

A

IBD and IBS

32
Q

gut microbiota of formula fed babies was low in?

A

bifidobacteria

33
Q

nutritionally, what are the significant microbial species?

A

strains classified as lactic acid bacteria

34
Q

two most commercially important strains?

A

streptococcus thermophilus and lactococcus lactis

35
Q

the 4 desriable probiotic properties?

A
  1. acid and bile tolerance
  2. adhesion to mucosal/epithelial surfaces
  3. antimicrobial
  4. bile sale hydrolase activity
36
Q

largest sales of probiotic foods

A

yogurt

37
Q

severe form of antibiotic-associated diarrhea

A
pseudomembranous colitis (caused by C. diff)
- treated with L rhamnosus and S. boulardii
38
Q

most common cause of acute infantile diarrhea?

A

rotavirus

39
Q

lactose intolerance

A

beta-galactosidase df (genetic)

40
Q

pelvic radiotherapy damaging the mucosa may cause?

A

acquired beta-galactosidase df