Chapter 1 Fundamentals of Clinical Dermatology: Morphology and Special Clinical Considerations Flashcards Preview

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Flashcards in Chapter 1 Fundamentals of Clinical Dermatology: Morphology and Special Clinical Considerations Deck (20):
1

Accurately identifying _________ is an essential step in generating a differential diagnosis

morphology

2

In taking a history from a patient presenting with a new skin complaint, the physician’s primary goal is to ________________, with a secondary goal of ________________________

establish a diagnosis
evaluating the patient as a candidate for therapy

3

________________ on the buccal mucosa in lichen planus, for instance

__________ are a sign of sun damage and suggest the need for improved sun pro- tection

Wickham’s striae
lentigines

4

Certain lesions, especially pigmented lesions, are best examined with a ________ to identify characteristic concerning features

dermatoscope

5

flat-topped or planar papules and plaques tend to be processes affecting the _______ and___________, while dome-shaped or nodular lesions often exhibit deeper infiltration into the ______ or _______

epidermis and superficial dermis
dermis or subcutis

6

The combination of primary morphology and secondary change (or absence of secondary change) determine a diagnostic category, also known as the “___________.”

reaction pattern

7

_______, also sometimes included under the heading of nodule, may be used to describe a more irregularly shaped mass, benign or malignant

Tumor

8

Fissures frequently occur on the palms and soles where the thick ________ is least expandable

stratum corneum

9

______ - Densely adherent scale with a sandpaper texture.
______ - Scale is shiny with a sheet-like desquamating edge, like peeling paint

Gritty
Shellac-like

10

___________ induce melanin production in the overlying epidermis, often leading to brown color overlying the focus of mast cells in the _______

Mast cells
dermis

11

Melanin in the dermis, either within melanocytes or extracellular, may appear brown, gray, or blue. This gray-blue color results from the “____________,”

Differentiation between epidermal and dermal melanin also can be aided by a _______, which accentuates epidermal but not dermal melanin

Tyndall effect
Wood lamp

12

black color - Intraepidermal hemorrhage (pathology) --> ____________ (example)

yellow color - Histiocytic inflammation (pathology) --> ___________ (example)

talon noir

Necrobiosis lipoidica

13

True red is often associated with ____________ (as seen in cellulitis or _____________);

Granulomatous brown (______________, marked by the classis “apple jelly” color

neutrophilic inflammation
Sweet syndrome


sarcoidosis

14

Resembling a straight line; often implies an external contactant or _______ phenomenon has occurred in response to scratching; may apply to a single lesion (such as a scabies burrow, _____________, or _____________)

Koebner
poison ivy dermatitis, or bleomycin pigmentation

15

________ - Having multiple angulated edges, resembling a star; example -->
Eschar overlying stellate purpura --> ________

Stellate
calciphylaxis

16

________ --> Like marble cake, with 2 distinct colors interspersed in a wavy pattern; usually seen in mosaic disorders in which cells of differing genotypes are interspersed (incontinentia pigmenti, ______________, linear and whorled nevoid hypermelanosis).

Whorled
hypomelanosis of Ito

17

Lying along the distribution of a lymph vessel; implies an infectious agent that is spreading centrally from an acral site. --> _________
When individual papules or nodules lie along the distribution of a lymphatic network, this pattern is termed ___________

Lymphangitic
Sporotrichoid

18

______________ -->
Horny plugs at the undersurface of scale removed from a lesion; seen in __________

carpet tack sign
chronic cutaneous lupus

19

_______________ -->
Transient induration of a lesion or piloerection after rubbing; seen in __________

Pseudo-Darier sign
congenital smooth muscle hamartoma

20

________________ --> a rumpled rim of epidermis hanging from the erosion’s edge

“mauserung” desquamation