Enzymes in general Flashcards
What are some primary regulators of enzyme activity?
Ph, temperature, substrate availability, product removal, cofactor availability.
What are allosteric enzymes?
They have two different binding sites, one catalytic and one allosteric site. The allosteric effector molecule binds to the allosteric binding site, thereby increase or decrease the enzyme activity.
Enzymatic reaction Coenzyme A participate in:
Entity transferred: Acyl groups
Enzymatic reaction NAD+, NADP+, FMN, FAD, coenzyme Q participate in:
Entity transferred: Hydrogen atoms, electrons
Enzymatic reaction TPP(thiamine pyrophosphate) participate in:
Entity transferred: aldehydes
Enzymatic reaction Biotin participate in:
Entity transferred: Carbon dioxide
Enzymatic reaction Tetrahydrofolate participate in:
Entity transferred: One carbon units
Enzymatic reaction pyridoxal phosphate participate in:
Entity transferred: Amino groups
Where do you find the glycolytic enzyme system?
Cytosol
Where do you find the enzymes concerned in oxidation pyruvate and fatty acids?
mitochondria
Which is the most highly enzyme system? (multienzyme systems)
It is the large supramolecular structures connected to membranes, like the respiratory chain where the enzymes are attached to the membrane of the mitochondria.
Enzymes in the nucleus?
DNA polymerase, DNA ligase and RNA polymerase.
Mitochondria: enzymes located in the outer membrane:
Acyl Coa synthetase
Mitochondria: enzymes located in the intermembrane space
Adenylate kinase
Mitochondria: enzymes located in the inner membrane
Enzymes of respiratory chain, oxidative phosphorylation, carnitine fatty acyl transferase, betahydroxybutyrate dehydrogenase
