Erythema multiforme Flashcards
What is the pathogenesis of erythema multiforme
A reaction of blood vessels in the dermis
What are some causes of E.M.
EM minor, mostly HSV, Mycoplasma
EM major Most drug reactions: Sulphonamides, Phenytoin, Barbitrates, Penicillin.
Erythema multiforme major symptoms
Severe skin and always mucous membrane involvement. Tendency for lesions to become confluent and form SJS or TEN.
Conjunctivitis, keratitis, tracheitis, meningitis, renal injury, GI injury.
What is erythema nodosum
an inflammatory reaction pattern of subcutaneous fat, forming painful subcutaneous nodules, usually on the lower legs.
What does erythema nodosum look like
Looks like erythema, feels like a node.
What causes Erythema nodosum
Many kinds of infections - streptococccal throat and respiratory infections
Mycoplasma pneumonia
Sarcoidosis
Tuberculosis
Drugs: OPCs, usually after recently starting. NSAIDs,
IBDs, ulcerative colitis and Crohns.
