Exam 1 Flashcards
what does the body’s need for a specific hormone depend on
- Physiological state
- individuals sensitivity to a hormone
- Simultaneous action of there chemical messengers on the same cell
a. additive effect
b. Synergism
c. Antagonist
Explain what down regulation is
binding of a hormone with its target cell receptor , often inactivation of some of the receptor molecules or decreased production of the molecules
T/F modified amino acids have norepinephrine, epinephrine, serotonin and dopamine and they have electrical charges that are destroyed slowly within time
False- they are rapidly destroyed in the blood
T/F Peptides are long sequence of amino acids and have electrical charges
False
they are short sequence
they survive for only a few seconds
Name the receptors that belong to which
- Cell Membrane
- Cell Cytoplasm
- Cell nucleus
- Membrane = protein, peptide and catecholamine
- Cell Cytoplasm = Steroids
- Cell nucleus = thyroid hormones ( thyroxine, triiodothyronine)
Which variables do not change their set points
- pH
- Osmotic Pressure
- Ion concentrations of calcium, sodium and potassium ions
which variables constantly change set points
- hormone levels
- nutrient levels
- blood pressure
- heart rate
which variables change set points with Diurnal rhythms
- temperature
2. Hormone Levels
which variables change set points change set points in response to pathological conditions
- temperature
- hormone levels
- cytokines
which variables change set points in response to reproductive state
- Temp
- Cytokine
- hormone levels
- C02 levels
- glucose
T/f multiple hormones are in need in order to trigger several changes in one cell
False- only need one hormone ( one hormone can have many target organs )
name the hormones that can cross the cell membrane and therefore are lipid soluble
- Steroids (most powerful)
- Sterols
- Thyroid hormones
the above hormones can interact with nuclear proteins and DIRECTLY influence Gene expression
Which hormones can have gene expression
- steroids
- sterols
- thyroid hormones
Name which steroid derived organ is secreted by:
- Adrenal
- Ovaries
- Testes
- placenta
- cortisol and aldosterone
- estrogen and progesterone
- testosterone
- estrogen and progesterone
Name the hormones that cannot cross the cell membrane and are lipid insoluble
- amino acide derivatives
- proteins
- Eicosanoids
- Prostaglandins
- leukotrienes
T/F non lipid soluble hormones can not bind to a membrane bound receptor on the outside of the cell and work through the second messenger system
False- they have to duhh cuz they can’t get in that shit on its own
true false
steroids can break through the cell membrane however they are not able to reach the nucleus of the cell
False- they totally can
since they can reach the nucleus- they are capable of acting directly on the DNA and influence specific gene transcription to messenger RNA - then can activate transcription ,enhance or inhibit
True/ False
Steriod hormones are considered long term
True - may take hours to days to weeks
since it takes time for transcription of DNA code into RNA , translation of mRNA into protein etc