inhibitiorsnucleicacid Flashcards

1
Q

Effective against Gram (+) and Gram (-)

A

Rifampin, florinated quinolones (ciproflaxin, levo, moxi), and sulfonimades (sulfamethoxazole, sulfisoxazole, sulfadiazine)

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2
Q

Effective against only gram (+)

A

fidaxomicin,

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3
Q

Treat UTI’s or infections of lower urinary tract

A

Nitrofuranoin, Fluorinated Quinolones

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4
Q

Cause red tears

A

Rifamycin

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5
Q

Bacteriostatic drug that inhibits nucleic acid synthesis

A

Sulfonamides (sulfamethoxazole, sulfisoxazole, sulfadiazone)

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6
Q

Inhibts folate pathway

A

Trimetorpim

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7
Q

Effective against anaerobes

A

metronidazole

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8
Q

Drug to avoid during pregnancy

A

metronidazole, Florinated quinolones

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9
Q

Broad treatment for UTI, salmonella, shigella, and pneumocystis

A

Trimethoprim

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10
Q

Used with Trimethoprim if bacteria synthesize their own folate

A

Sulfonmides

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11
Q

Used against parasites, anaerobes and Cdiff

A

Metrozidazole

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12
Q

Binds/inhibits topo II and topo IV, cause ds DNA breaks

A

Flourinated quinolones (flax drugs)

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13
Q

some of the broadest inhibitors of nucelic acids

A

Fluorinated Quinolones

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14
Q

Used to treat biological warfare

A

Ciprofloxacin

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15
Q

These drugs acquires resistance by incrased production of PABA

A

Sulfonamides

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16
Q

Causes a disulfriam like reaction

A

Metronidazole

17
Q

this percent of UTI’s are from E. coli

A

75-95%

18
Q

drug is toxic to liver

A

rifampin

19
Q

these drugs cannot be taken with Calcium

A

Fluorinated Quinolones

20
Q

Drug(s) cause hemolysis in G 6-P DH deficiency

A

Nitrofurntion and Sulfonamides

21
Q

liver damage will lead to higher serum levels of this drug

A

Rifampin