Leprosy

Question 0

pathognomonic leprosy

Answer 0

invasion and destruction of nerves in the dermis by T cells

Question 1

positive lepromin

Answer 1

tuberculoid leprosy

Question 2

CD4 > CD8

Answer 2

tuberculoid leprosy

Question 4

symmetric peripheral neuropathy

Answer 4

lepromatous leprosy

nerve enlargement and damage are symmetric and result from actual bacillary invasion

Question 5

have a predominant Th1 response

Answer 5

tuberculoid leprosy

Question 6

In leprosy, measure of the number of acid fast bacilli scrapings that stain uniformlybright

Answer 6

Morphologic index

Question 7

incubation period of M Leprae

Answer 7

2 to 40 years

Question 8

Explain the spectrum of leprosy

Answer 8

TT BT LT LL

Question 9

Skin lesions of tuberculoid leprosy

Answer 9

one or few hypo pigmented macules or plaques

Question 10

Late manifestations of lepromatous leprosy

Answer 10

Loss of eyebrows and lashes
pendulous earlobes
dry scaling skin

Question 11

Type 1 lepra reactions

Answer 11

Downgrading and reversal reactions

Question 12

Nerve trunk most common affected in downgrading and reversal reactions

Answer 12

ulnar nerve at the elbow

Question 13

The most dramatic manifestation of Type 1 lepra reactions

Answer 13

footdrop

Question 14

When type 1 lepra reactions precede the initiation of appropriate antimicrobial therapy

Answer 14

downgrading reactions

Question 15

The most characteristic microscopic feature of Type 1 lepra reactions

Answer 15

edema

Question 16

Type 2 lepra reaction

Answer 16

Erythema nodosum leprosum (ENL)