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Skin > McGuffin Skin Part 1 > Flashcards

McGuffin Skin Part 1 Flashcards

1
Q

what are the functions of the skin

A 
absorption
protection
sensation
temperature regulation
vitamin D production
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2
Q

epidermis is derived from what

A

ectoderm

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3
Q

what is the most superficial part of the skin

A

epidermis

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4
Q

the dermis is derived from what

A

mesoderm

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5
Q

the hypodermic is derived from what

A

mesoderm

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6
Q

what are rite ridges

A

epithelial extensions that project into the underlying connective tissue and mucous membranes

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7
Q

the lung, liver, pancreas, digestive tubes are all derived from what

A

endoderm

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8
Q

where is thick skin found

A

palmar surface of hands and fingers

plantar surface of the feet and toes

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9
Q

in thick skin what is actually thicker

A

epidermis- specifically stratum corneum

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10
Q

the stratum lucidum is found where

A

found in thick skin only

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11
Q

what type of skin has lots of sweat glands

A

thick skin

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12
Q

what type of skin has many hair follicles and melanocytes

A

thin skin

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13
Q

meissner corpuscles respond to what

A

slow vibration

texture

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14
Q

merkel cells respond to what

A

sustained pressure

touch

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15
Q

pacinian corpuscle responds to what

A

deep pressure

fast vibration

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16
Q

ruffini endings respond to what

A

sustained pressure

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17
Q

what sense organs response to sustained pressure

A

merkel cells and ruffini endings

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18
Q

what sense organ appears as an onion

A

pacinian corpuscle

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19
Q

what sense organ is only found in thick skin

A

merkel cells

20
Q

merkel cells contain what in basal cytoplasm?

A

dense-core neurosecretory vesicles

21
Q

what is the outermost later of epithelium

A

stratum corneum

22
Q

what is desquamation?

A

the flaking off of dead keratinocytes appear as flattened keratinized flakes or squames of keratin

23
Q

what layer of the epidermis provides the wearing surface for the skin

A

stratum corneum

24
Q

what layer of the epithelium is a thin layer only present in thick skin

A

stratum lucidum

25
Q

what layer is a continuation of differentiation of keratinocytes from the stratum granulosum

A

stratum lucidum

26
Q

what layer do the keratinocytes become flattened

A

stratum granulosum

27
Q

where are keratohyalin granules formed

A

stratum granulosum

28
Q

what is a keratohyalin granule

A

synthesized from bundles of keratin cross-linked with filaggrin

29
Q

what gives the darkly basophilic granular appearance to the stratum granulosum

A

karatohyalin granules

30
Q

what do lamellar bodies do in the stratum granulosum

A

release lipid into intercellular spaces which seals the spaces b/w cells for waterproofing

31
Q

what layer of the epidermis is made up of squamous epithelial cells known as keratinocytes

A

stratum spinosum

32
Q

how are keratinocytes held together

A

desmosomes

33
Q

what gives the stratum spinosum the spindly kill cytoplasmic projections

A

intercellular bridges made by desmosomes

34
Q

desmosomes are also called what

A

macula adherens

35
Q

langerhan cells are what

A 
immune cells derived from monocytes
function as antigen presenting cells
36
Q

langerhan cells are found in what layers of the epidermis

A

all but mostly stratum spinosum

37
Q

what is keratin

A

protective protein made by keratinocytes

38
Q

lamellar bodies are waht

A

lipid-filled non-embrace bound structures synthesized by keratinocytes and stacked as lamellae

39
Q

what are melanin granules

A

pigments synthesized by melanocytes and taken up by keratinocytes

40
Q

stratum basale is made up of what

A

a single of cuboidal cells that attach to the basement membrane

41
Q

how is the stratum basal attached to the basement membrane

A

hemidesmosomes

42
Q

what cells are found in the stratum basale

A

keratinocyte stem cells

melanocytes

43
Q

melanin is synthesized from what

A

tyrosine

44
Q

melanocytes are derived from what

A

embryonic neural crest cells

45
Q

what are the forms of melanin

A

pheo-melanin: red-yellow

eu-melanin: brown-black

46
Q

what is the purpose of melanin

A

its protects DNA by absorbing the scattering UV radiation

Skin (12 decks)

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