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Oncology > Molecular Biology, Genetics and Immunology of Cacncer > Flashcards

Molecular Biology, Genetics and Immunology of Cacncer Flashcards

1
Q

The 4 Bases of DNA

A

Adenine
Thymine (In mRNA Uracil)
Guanine
Cytosine

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2
Q

2 categories of cancer genes

A

Dominant: proto-oncogenes
Recessive: tumor suppressor

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3
Q

Gain-of-function mutations

A

altered or unregulated activity of a “proto-oncogene” leads to tumorigenesis

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4
Q

Loss-of-function mutations

A

loss of activity of tumor suppressors results in unregulated pathways and tumorigenesis

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5
Q

Type of cell that tumors originated from

A 
Carcinoma- epithelial cells
Sarcoma-  connective tissue cells
Lymphoma and Leukemia- blood stream
Germ cell tumors- Testicle and ovary
Blastomas- immature cells or embryonic tissue
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Oncology (8 decks)

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