Oncology Document

Question 1

Acanthosis nigricans finding

seen in __ ares

common in ____

also a

Answer 1

hyperpigmented, velvety plaque

intertriginous (axilla)

insulin resistant states

paraneoplastic, internal malignancy

Question 2

Amyloidosis

secondary is a rare cause of

Chloroma

typically ___ colored, due to

reflects

manifestation of

Answer 2

macroglossia

soft tissue mass

green, MPO

extramedullary myeloblastoma (collection of granulocytic precursors)

AML

Question 3

1/3 Dermatomyositis pt have

Hyperviscositiy syndrome occurs w
H
H

pt presents w

physical findings

Answer 3

internal malig

high level paraproteinemia (MM, waldenstroms macroglobulinemia)
Hyperleukocytosis from AML/polycythemia

mucosal bleeding, vis impair, AMS, CV findings

bleeding diathesis (Echymoses), retinal vein engorged/segmented

Question 4

Sign of Lesar trelat process

finding

reflects

Sister Mary Jane’s Nodes aka

seen in pt w

Answer 4

paraneoplastic

abrupt appearance of multiple seborrheic keratosis

internal malig

periumbilical adenopathy

ab/pelvic neoplasm (ovarian ca)

Question 5

SVC syndrome can be due to

Sweet Syndrome aka

typically have

Answer 5

mediastinal adenopathy (lung ca, lymphoma)

acute febrile neutrophilic dermatosis

malignancy (leukemia)

Question 6

Tripe hand presents w

typically indicates

Trousseas sign

setting of, such as

Answer 6

thickened, velvety white palmar skin

cancer

superficial thrombophlebitis

malignancy, panc carcinoma

Question 7

Unilateral scleral icterus from

ocular melanoma results in

propensity for

Virchow’s node aka

malignant in indiv >
indicates ca below

common sites

Answer 7

metastatic melanoma

eye enucleation, glass prosthesis

liver mets

supraclavicular LAD

40
diaphragm

gastric, panc, prostate, teste