Y&A: 8 Valvular Heart Disease Flashcards Preview

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Flashcards in Y&A: 8 Valvular Heart Disease Deck (6)
1

What are the major etiologies of aortic stenosis? Aortic insufficiency?

AS: More commonly acquired (i.e. progressive calcification or rheumatic fever), less commonly bicuspid valves

AI: Acquired (i.e. bacterial endocarditis, rheumatic heart disease); connective tissue disorders

2

What are the major etiologies of mitral stenosis? Mitral regurgitation?

MS: Almost always rheumatic fever; other less common causes are SLE, carcinoid, congenital defects

MR: Primary leaflet dysfunction (i.e. bacterial endocarditis or connective tissue disorders), Annular dilation (i.e. ventricular dysfunction/dilation), MV prolapse or rupture of papillary muscles, ischemic heart disease

3

What changes does aortic stenosis have on the chambers of the heart?

LV: LaPlace's law: wall tension = Pressure * radius / (2 * wall thickness)
Thus, increased pressure = increased wall tension on LV which causes PARALLEL duplication of muscle fibers --> concentric hypertrophy to normalize wall tension (increased wall thickness)

4

What changes does aortic insufficiency have on the chambers of the heart?

LV: diastolic volume overload --> SERIES duplication of muscle fibers --> eccentric hypertrophy and LV dilation --> can cause MV annular dilation --> MR --> LA dilation

5

What changes does mitral stenosis have on the chambers of the heart?

LA: elevation in pressures leads to hypertrophy and eventual dilation --> increases risk of A. fib/PACs
LV: pressure and volume underloaded, especially if the patient is no longer in sinus rhythm 2/2 LA dilation
RV: increased PVR (can be permanent) from pulmonary vessel overload

6

What changes does mitral regurgitation have on the chambers of the heart?

LV: volume overloaded with a volume going to the high-compliance, low pressure LA (versus the low-compliance, high pressure arterial system) --> eccentric hypertrophy
LA: volume overloaded (as above) --> dilation (if sudden --> pulmonary vein engorgement --> RV issues)