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Thomas Monk
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Decks in this class (21)
1. Tumour supressor genes
How do mutations in tsgs contribu...,
What are the main ways that tsgs ...,
What s the clinical background of...
12
cards
2. Oncogenes
What is the role of oncogenes 1,
How do point mutations activate o...,
How does amplification activate o...
8
cards
4. Colorectal Cancer - HNPCC, FAP, MUTYH
What causes lynch syndrome 1,
What cancers are caused by hnpcc 2,
What s the contribution of each g...
25
cards
5. Breast Cancer
What factors complicate the diagn...,
What is the major role of brca1 a...,
What is the clinical consequence ...
18
cards
6. Neurofibromatosis Type 1 and 2
What is the clinical phenotype of...,
What is the role of nf1 2,
How is nf1 inherited 3
8
cards
7. Tuberous Sclerosis
What causes tsc 1,
What is the role of the tumberous...,
How is the phenotype of tsc chara...
6
cards
8. Other cancer syndromes
What genes are involved in men an...,
What is the clinical phenotype of...,
What is the role of men1 3
16
cards
9. Examples of cancer pathways
What is the result of mutations i...,
What is the ras mapk pathway and ...,
What are the 4 major mapk cascade...
17
cards
10. DNA damage response and cancer
Why is dna constantly damaged 1,
What does mismatch repair recogni...,
What genes are involved in mmr 3
3
cards
12. Pharmacogenetics dose determination and immune response
What are the 3 main reasons for p...,
What are the benefits of pgx 2,
Which genes contribute to variati...
10
cards
14. Genetics of AML
What type of cells proliferate in...,
How is aml diagnosed 2,
What are the 2 types of core bind...
27
cards
15. Genetics of CML
What type of cells proliferate in...,
What are the clinical symptoms of...,
What characterises cml genetically 3
19
cards
16. Genetics of ALL
What type of cells accumulate in ...,
What are the main types of all an...,
What are the symptoms of all 3
28
cards
17. Mature B-cell neoplasms
What is the difference between cl...,
How is cll characterised at the c...,
Which cytogenetic techniques are ...
22
cards
18. Genetics of lymphoma
How is lymphoma characterised 1,
How is hodgkin s lymphoma charact...,
What is the main risk factor for ...
22
cards
19. Genetics of myelodysplastic syndromes
What 4 factors characterise mds 1,
Which cell lineages can be involv...,
Why is mds considered pre maligna...
21
cards
25. Strategies of MRD monitoring
What is mrd 1,
What is the purpose of mrd 2,
How is mrd monitored in aml 3
17
cards
27. Myeloid proliferative disorders
What type of genes are implicated...,
How are mpns characterised 2,
What type of cells accumulate in ...
17
cards
Lung cancer
What are the most common oncogeni...,
Why is egfr tested in nsclc 2,
What is the consequence of egfr m...
17
cards
ctDNA
What is ctdna 1,
How does ctdna differ from other ...,
What are the advantages of testin...
7
cards
Other solid tumours (CRC, melanoma, ES)
How are ffpe samples prepared for...,
What cancers is braf commonly mut...,
What is the role of braf 3
29
cards
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6: Cancer genetics and treatment
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