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Decks in this class (11)
MT L1 Antimetabolites - Folate & pyramidine "antagonists"
Name the 4 main groups of antimet...,
Antimetabolites inhibit one or mo...,
Name the 3 enzymes in the folate ...
19
cards
MT L1 Antimetabolites - Purine "antagonists"
Name 3 purine antagonists,
Pathway of activation of 6mp and 6tg,
What does the enzyme hprt stand for
7
cards
MT L1 Antimetabolites - Sugar-modified nucleosides
Name three sugar modified neucleo...,
Why is gemcitabine 100x more pote...,
What are the 2 enzymes that prodi...
6
cards
MT L2 Mitotic spindle poisons
What are microtubules,
Microdubules are assembalies of e...,
How do tubulin dimers work
19
cards
MT L3 New targets
5 new targets,
What sort of lesions radiotherapy...,
Repair bathways
19
cards
AT L1 DNA alkylation
Why use compounds in combination,
Explain neuclotide excision repair,
What sort of damage does parp repair
14
cards
AT L1 Minor groove binders
Name 3 covalent minor groove binders,
Name 2 non covalent minor groove ...,
What is the shape of a minor groo...
25
cards
AT L2 DNA strand breakers - bleomycins
What are bleomycin,
S e of belomycins,
How do bloemycins work
11
cards
AT L2 Platinums
How are platinums activated,
3 mechanisms of drug resistance t...,
2 mechanisms of drug resistance o...
6
cards
AT L2 Platinums - the drugs
Developments in the 70s,
Developments in the 80s,
Developments in the 90s
5
cards
AT L3 Intercalators
2 drugs that target topoisomerase...,
How do drugs target top2,
Problem with anthracycline
17
cards
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Cancer MT & AT
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