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Amila Suleman
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Decks in this class (22)
Introduction
0
cards
L1 + L2: Drug discovery and development pipeline
The stages of the pipeline and th...,
Drug discovery and development pi...,
Therapeutic concept 3
10
cards
L1 + L2: Drug discovery and development pipeline part 2
Lead optimisation 1,
Physical properties 2,
A note on log p and d 3
10
cards
L1 + L2: Drug discovery and development pipeline part 3
The place of clinical trials in d...,
Regulatory approval 2,
Regulatory documentation 3
4
cards
L3: Measuring agonist and antagonist activity
Homeopathy 1,
Homeopathic dilution best and wor...,
Definition of drugs and natural s...
10
cards
L3: Measuring agonist and antagonist activity part 2 (there is more)
Agonist a binding 1,
Hill langmuir equation 2,
What us an agonist 3
10
cards
L4: pharmacokinetics
Pk vs pd 1,
Absorption and distribution 2,
Variability between drugs 3
12
cards
L5: Radioligand binding
What are rlb assays 1,
What can rlb assays determine 2,
Rlb and radioactivity 3
11
cards
L5: Radioligand binding part 2
Calculating specific binding 1,
Some calculations so better look ...,
Radioligand displacement assays 3
13
cards
L6: Drug metabolism
What makes an ideal drug 1,
Why might a nce be subject to dru...,
Where does drug metabolism occur 3
10
cards
L6: Drug metabolism part 2
P450 catalytic cycle 1,
C oxidation 2,
Non p450 drug metabolism 3
10
cards
L6: drug metabolism part 3
Age geriatrics and neonates 1,
Pro drugs 2,
L dopa 3
6
cards
L7: Receptors as drug targets
How can receptors be classified 1,
Receptor subfamilies 2,
Ion channel receptors 3
8
cards
L7: Receptors as drug targets part 2
Gpcr 1,
Intrinsic enzyme receptors 2,
Dna binding receptors 3
6
cards
L8: Safety pharmacology and toxicology
Safety pharmacology 1,
Primary and secondary pharmacodyn...,
Dosage 3
10
cards
L8: Safety pharmacology and toxicology part 2
Regulatory requirements ich guida...,
Regulatory studies 2,
Attritition 3
3
cards
L10: Biological drugs
What are biologicals 1,
Variolation 2,
Early biologicals 3
10
cards
L10: Biological drugs part 2
Mechanisms of actions of antibodi...,
Evolution of therapeutic antibodi...,
Next generation therapeutic antib...
9
cards
L11: Clinical trials
What are clinical trials 1,
Target of a clinical trial 2,
Patients and clinical trials 3
10
cards
L11: Clinical trials part 2
Phase 2 1,
One or two stage designs 2
2
cards
Schild plot
Competitive antagonists 1,
A measure of rca affinity 2,
How to obtain pa2 3
6
cards
L5 RADIOLIGAND CALCULATIONS
How do you calculate specific bin...,
Metric prefixes 2,
Radioactivity conversions 3
5
cards
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