Integrated Physiology and Adaptation To Physical (in) Activity

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Decks in this class (8)

The biology of muscle damage and remodelling
-Define exercise-induced muscle ‘damage’ (EIMD) -Explain the characteristics and temporality of muscle damage/repair -Discuss the mechanisms that co-ordinate muscle remodelling following acute damage – Including classical theories and novel hypotheses -Place evidence from multiple model organisms into a physiological context of human muscle repair
20  cards
Metabolic and molecular basis for adaptation to resistance-type exercise
-What is resistance (type) exercise, and what are the major adaptations it elicits? Why is it critical for us to understand how resistance training leads to adaptation? -What are the responses to a single bout of resistance-type exercise at different levels of physiology: o Physiological (protein metabolism) o Cellular (cellular protein turnover and role of satellite cells) o Molecular (anabolic signalling pathways) -How do these acute responses accumulate into adaptation?
17  cards
Metabolic and molecular basis for adaptation to endurance-type exercise
-What is endurance (type) exercise, and what are the major adaptations it elicits? Why is it critical for us to understand how endurance training leads to adaptation? -What are the responses to endurance-type exercise at different levels of physiology: o Physiological (e.g. aerobic capacity and cardiac output) o Cellular (e.g. cardiac remodelling, angiogenesis, mitochondrial biogenesis) o Molecular (e.g. cellular signalling pathways regulating the above events) -How do these acute responses
15  cards
Physiological and molecular mechanisms underlying the adaptation to physical inactivity
-What do we mean by physical inactivity and ‘disuse’ and what are the major adaptations it elicits? -Why is it critical for us to understand how inactivity results in deconditioning? -What factors influence the rate of disuse induced deconditioning? -What are the responses to physical inactivity or disuse at different levels of physiology: o Physiological o Cellular o Molecular
18  cards
Modern molecular biology and the prediction of human physiology, disease and performance
-Discuss the principles and application of Western blot and immunofluorescence analysis -Explain the concept and principles underlying ‘omics’ analyses -Understand how ‘omic’ approaches can facilitate understanding of adaptation to activity – Including examples from recent literature
23  cards
Sarcopenia: age-related declines in skeletal muscle
-Background to muscle mass maintenance: o Describe why muscle is important o Explain how muscle mass is regulated in healthy individuals and how we can measure this -Apply to sarcopenia: o Describe sarcopenia and its clinical manifestations o Discuss the molecular and metabolic alterations that underpin sarcopenia o Consider how what we know from molecular studies inform interventional approaches -Emphasis on main stimuli of muscle growth: o Exercise o Nutrients
13  cards
Mitochondrial function adaptation to physical activity
The creator of this deck did not yet add a description for what is included in this deck.
20  cards
Vascular contribution to muscular health
-To understand the important role of blood flow in the circulatory system -To appreciate the relationship between blood flow, mean arterial pressure, cardiac output and total peripheral resistance -To understand the factors that govern total peripheral resistance via Poiseuille's law -To describe distinct vessel characteristics and functions across the cardiovascular system -To describe the dynamics and distribution of blood flow within body tissues at rest and in response to exercise, and t
23  cards

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