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Decks in this class (17)
nucleic acids and chromosomes
nucleic acid structure: explain the structure of DNA and RNA, list the bases found in DNA and RNA and indicate which ones are purines and which ones are pyrimidines
9
cards
nucleic acids and chromosomes
base pairing: explain melting and re-annealing of complementary strands of nucleic acids and what is meant by Watson-Crick base-pairing
3
cards
nucleic acids and chromosomes
nucleic acid analysis: explain the methods used to analyse nucleic acids, including hybridisation, the polymerase chain reaction (PCR) and the use of restriction enzymes
20
cards
nucleic acids and chromosomes
chromosomes: explain the packaging of DNA into nucleosomes and relate this to chromosome structure; summarise the human karyotype
7
cards
protein translation and post-translational modification
mechanism of translocation: summarise the mechanisms which ribosomes use to translate a mRNA sequence into a protein sequence, ensuring the fidelity of the genetic code
19
cards
protein translation and post-translational modification
prokaryotes versus eukaryotes: explain why some antibiotics inhibit protein synthesis in prokaryotes but not eukaryotes
2
cards
protein translation and post-translational modification
secretory pathway: explain the features of a newly-synthesised protein that are required for it to enter the secretory pathway
6
cards
protein translation and post-translational modification
post-translational modification: summarise the ways in which newly-synthesised proteins can be post-translationally modified
3
cards
DNA replication, the cell cycle and mitosis
mechanism of DNA replication: explain the reaction catalysed by DNA polymerases and the functions of the components of the replication complex, explain semi-conservative replication
6
cards
DNA replication, the cell cycle and mitosis
DNA replication fidelity: explain how accuracy is maintained by proof-reading, DNA repair and the use of RNA primers
2
cards
DNA replication, the cell cycle and mitosis
chromosome replication: summarise the replication of mammalian chromosomes, explain replication of the E. coli chromosome by drawing a diagram
3
cards
DNA replication, the cell cycle and mitosis
the cell cycle: define the different phases of the cell cycle, explaining how the chromosomes segregate at metaphase by drawing a diagram
6
cards
gene organisation, transcription and regulation
DNA versus RNA: explain the basic differences between DNA and RNA, explain what is meant by transcription
6
cards
gene organisation, transcription and regulation
RNA classes: list the major classes of RNA and the classes of RNA polymerases involved in synthesising each of these
2
cards
gene organisation, transcription and regulation
gene transcription: explain what is meant by the terms "gene promoter" and "transcription factor", explain with the aid of diagrams the processes involved in transcribing a eukaryotic gene
12
cards
gene organisation, transcription and regulation
mRNA processing: explain with the aid of diagrams the events that take place in pre-mRNA processing; define what is meant by the terms "splice donor site" and "splice acceptor site", the function of the spliceosome, and explain the addition of a "cap" and "poly A tail" to pre-mRNA
17
cards
gene organisation, transcription and regulation
gene regulation by small RNAs: explain the mechanisms underlying gene regulation through RNA interference, explain what micro RNAs (miRNAs) are and how they act in gene regulation
11
cards
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mcd nage
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