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andy Sitoh
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lecture 1
AIMS of the subject
- to develop an appreciation of how the cells of the nervous system are specialised for information processing, and how they combine to form circuits and networks.
- understand the structural and functional organisation of the human nervous system
- to understand how the nervous system can be studied and to appreciate the scope and limitations of different methods of examination and experimentation
20
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lecture 2
What were some ideas about the me...,
How was experimentation able to r...,
What was the big thing in the ear...
16
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lecture 3
Where is the nervous system?
27
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lecture 4
Development of the nervous system
34
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lecture 5
nervous system injury and repair
39
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lecture 6
Vision 1: the retina
- photoreceptors and phototransduction
- retinal circuitry
- ganglion cell function
- light is converted to a neural signal by photoreceptors: phototransduction
- information is carried in parallel down via bipolar cells to ganglion cells
- ganglion cells are tuned to encode edges
-- central part of the receptive field acts differently to the peripheral part
18
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lecture 7
Vision 2: central processing of vision
- targets of ganglion cells
- visual pathway
- extrastriate processing of visual information
-- dorsal pathway
-- ventral stream
18
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lecture 8
How is em radiation sensed by the...,
How is distortion of the skin sen...,
What does the somatosensory syste...
36
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lecture 9
Hearing
17
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lecture 10
gustation and olfaction: taste and smell
sensors that detect chemicals
- difference between olfaction and taste: contribution to flavour
- the 5 different tastes: role of taste buds and taste cells; sensory transduction
- central gustatory pathways
- role of olfactory receptor cells (neurons): receptive fields, sensory transduction, pathway
- role of olfactory bulb: mitral cells and granule cells
- central olfactory pathways
17
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lecture 11
Neural control of digestion
- a tale of multiple interacting systems and hierarchies
- roles of different regions of digestive tract
- components of digestive process regulated somatic NS and brain: where is control conscious
- components of digestive process regulated by ENS: types of neurons in ENS and their connections
11
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lecture 12
The lower motorneuron
24
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lecture 13
The upper motor neuron
20
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lecture 14
How many neurons does the cerebel...,
What are the basal ganglia,
Do the cerebellum and basal gangl...
21
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lecture 15
Language
when do humans begin to use language?
which brain regions are required for language?
do only humans use "generative" language?
why is human language unique?
when did humans begin to use language?
what brain mechanisms underlie human language?
15
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lecture 16
Homeostasis
20
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lecture 17
Rule #1: Most organs receive input from the autonomic nervous system
- not all organs receive input from both e.g. many blood vessels - SNS only
Rule #2: the autonomic nervous system consists of two neurons connected in series
- the neuron innervating the target occurs outside the central nervous system
Rule #3: the axons of sympathetic preganglionic neurons are short.
- the ganglionic axons project long distances to contact the target tissue
Rule #4: the axons of parasympathetic preg
31
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lecture 18
Motivation
- behaviours (motor activation) occur in response to:
-- reflex stimulation – dropping a hot object – automatic
-- conscious or willful command (motivated behaviour)
- motivated behaviour occurs in response to the body's absolute requirements
-- eating when hungry
- or by abstract things
-- reading a book, going for a swim
- motivation = driving force on behaviour
36
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lecture 19
pain
18
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lecture 20
Learning and Memory I
- different types of memory
- distinction between explicit and implicit memory – subdivisions of these
- nature of working memory and key regions involved
- role of hippocampus and neocortex in formation and recall of long term explicit memory
- how memory is organised and stored
9
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lecture 21
molecular mechanisms of memory
- roles of LTP and LTD in memory storage
- mechanisms responsible for LTP and LTD (ch 7)
- role of calcium-calmodulin dependent protein kinase II in dendritic spines
- mechanisms regulating Ca2+ entry into cytoplasm
11
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lecture 22
What information about the brain ...,
What do the tissues of the nervou...,
What techniques are used to view ...
10
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lecture 23
How should the brain be studied,
What can be determined about brai...,
What are cranial nerves
19
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lecture 24
What do you need to know,
What is the basic determination o...,
What are the principal sex hormones
13
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lecture 25
What is tree of life,
In what way do vertebrate brains ...,
How best to measure brain size
19
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lecture 26
Which regions of the cat brain ar...,
How can emotional systems develop,
How can emotional systems become ...
17
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lecture 27
How do addictive hedonic drugs af...,
What was a significant advance li...,
What is the vta
13
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lecture 28
How many people are affected by m...,
How does who classify the most si...,
What is the distinction between m...
23
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lecture 29
What is abuse induced brain trauma,
What evidence exists of the impac...,
What is the critical period
16
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lecture 30
What is an absolute requirement o...,
What guidessocial behaviour,
With what is the prefrontal corte...
22
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lecture 31
What else does our big brain do,
How can we break prefrontal corte...,
What is the function of the dorso...
18
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lecture 32
What is the process of insight,
What is proof by contradiction,
What is cantor and infinity
17
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lecture 33
What are mental disorders,
What are the most significant men...,
What are further categories of bi...
28
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lecture 34
What are some particularly powerf...,
Why do people use recreational or...,
What aspects of brain function do...
22
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lecture 35
How does the brain produce our ex...,
How can there be any sort of awar...,
What is the chinese room thought ...
16
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(Molly) NEUR30003 - Principles of Neuroscience
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