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Brooke Thornburg
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Decks in this class (31)
Lecture 1: Med Chem
Drug 1,
Biologics 2,
Biological activity of a receptor...
18
cards
Lecture 2: Ionization of Drugs
Ionization state 1,
Charged molecules 2,
Ph 3
32
cards
Lecture 3: membrane permeability and partitioning of drugs
Hydrophilic groups 1,
Hydrophilic functional groups 2,
Hydrophobic groups 3
48
cards
Lecture 4: Electronic Effects in Drugs
Electronegativity 1,
Resonance 2,
Electronegativity effect on ioniz...
35
cards
Lecture 5: Drug-receptor stereochemistry
Arnaldo piutti 1,
L asparagine 2,
D asparagine 3
33
cards
Lecture 6: Drug-receptor Energetics
Drug shape 1,
Hydrophobic interactions determine 2,
Charge charge interactions and h ...
41
cards
Lecture 7: QSAR and Drug Development
Qsar quantitative structure activ...,
Molecular descriptors 2,
Molecular descriptors examples 3
27
cards
Mod 2: Pharmacodynamics
0
cards
Lecture 1: Pharmacodynamics
Pharmacology 1,
Pharmacodynamics 2,
Pharmacokinetics 3
31
cards
Lecture 2: Drug-receptor Interactions
Nature of drug receptors 1,
Quantitative aspects of dr intera...,
Selectivity of drug action 3
30
cards
Lecture 3: Response, Potency and Efficacy
Agonist 1,
Antagonist 2,
Potency 3
44
cards
Lecture 4: Receptor Antagonism
Receptor antagonism 1,
Three types of antagonists 2,
Competitive antagonism 3
5
cards
EXAM 2 VOCAB
Pharmacology 1,
Pharmacodynamics 2,
Pharmacokinetics 3
165
cards
Lecture 1: Intro to ADME
Adme 1,
How to quantify drug effect 2,
Dosage form to effect 3
23
cards
Lecture 2: Drug Absorption
Factors determining movement of d...,
Small intestine 2,
Folds of kerckring 3
36
cards
Lecture 3: Distribution
Concentration vs time cuves drug ...,
Concentration vs time cuves drug ...,
What causes the offset of the pha...
33
cards
Lecture 4: Excretion
Major routes of excretion 1,
Other routes of excretion 2,
Nephron 3
32
cards
Lecture 5: Hepatic Elimination
Hepatic elimination consists of 1,
Enterohepatic cycle 2,
Portal vein 3
39
cards
Lecture 6: Metabolism
Metabolism importance 1,
2 reasons metabolism is important...,
Largest means of elimination of d...
32
cards
Lecture 7: Metabolism
Cyp450 induction mechanism 1,
Induction cross talk 2,
Inducers cause a wider array of d...
39
cards
Lecture 8+9: Toxicology
Toxin 1,
Toxicology 1,
Toxicant 2
24
cards
Lecture 10: Toxic drug reactions
Adverse drug reactions 1,
Side effects 2,
Augmented response 3
15
cards
Lecture 11: Drug-induced hypersensitivity reactions
Drug induced hypersensitivity dihr 1,
Key characteristics of dihr 1,
Determinants of dihr 2
12
cards
Exam 4
0
cards
Lecture 1+2: Cell Injury
Cellular responses to stress and ...,
Homeostasis 2,
Adaptation 3
82
cards
Lecture 3+4: Acute and Chronic Inflammation
Inflammation 1,
Inflammation damaging normal tiss...,
Pharmacological approaches to inf...
70
cards
Lecture 5: Infectious Diseases
Host microorganism interactions 1,
Commensalism 2,
Mutualism 3
44
cards
Lecture 6: tissue renewal
Parenchymal cells 1,
Stromal cells 2,
Tissue regeneration 3
31
cards
Lecture 7: Shock and Edema
Shock 1,
Types of shock 2,
Distributive shock 3
19
cards
Lecture 8 + 9: Genetic Diseases
Single gene mendelian traits 1,
Cytogenetic disorders 2,
Single gene disorders with atypic...
60
cards
Neoplasia
Neoplasia 1,
Cancer tumors 2,
Nomenclature of benign tumor 3
101
cards
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PATHO
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