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tahi m
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Decks in this class (17)
L2: Translocation of drugs
What is pharmacokinetics 1,
What two main processes determine...,
What are the two major types of t...
32
cards
L3 drug absorption
What is meant by absorption in ph...,
Why is absorption especially impo...,
What is the difference between sy...
52
cards
L4 drug absorption pt2
What are the four main types of i...,
What is the fastest and most cert...,
What happens to drug concentratio...
90
cards
L5: Drug formulation
What is drug formulation 1,
What can drug formulation affect ...,
Name three formulation factors th...
56
cards
L6: Drug Distribution
What is drug distribution 1,
What four major factors determine...,
Which organs receive the highest ...
46
cards
L7: General principles of drug metabolism
What is xenobiotic metabolism 1,
What is the aim of xenobiotic met...,
What are the main sites of drug m...
25
cards
L8: CYP450 enzymes
What is the main function of cyto...,
Where are cyp450 enzymes mainly f...,
What gives cyp450 enzymes their n...
45
cards
L9: CYP450
What are cyp450 isoforms 1,
Why is identifying the specific c...,
Which three cyp isoforms are the ...
30
cards
L10 non-P450 mediaed phase I metabolism
What are the two main types of no...,
Name the non cyp enzymes involved...,
Name the non cyp enzymes involved...
45
cards
L11+12: Phase II Metabolism
What is the primary aim of phase ...,
Why is increased water solubility...,
What is the typical outcome of ph...
64
cards
Lecture 13 Enzyme Induction & Inhibitionin Drug Metabolism
Q how were cytochrome p450 enzyme...,
Q what happens when a drug induce...,
Q what are the clinical consequen...
40
cards
L15: Physiological & Pathological Factors Affecting Xenobiotic Metabolism
What is a key limitation in drug ...,
What is bilirubin and how is it n...,
Why are neonates susceptible to k...
56
cards
L16+17 Pharmacogenetics & Drug Metabolism
What is pharmacogenetics 1,
What types of genetic polymorphis...,
How frequently do polymorphisms o...
43
cards
L18+19: Renal excretion (rerevise)
What are the features of the filt...,
Describe the structure of podocyt...,
What are the only two things the ...
101
cards
L20: Transporters
What family does the p gp abcb1 t...,
What are key members of the abc t...,
What energy source does the abc t...
46
cards
L21+22: PK
What are the problems in dosing d...,
What factors affect drug effects 2,
What is the order of drug process...
104
cards
21+22
What does pharmacokinetics pk des...,
What does pharmacodynamics pd des...,
What is the relationship between ...
56
cards
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PED2001
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