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tahi m
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Decks in this class (18)
L2: Translocation of drugs
What is pharmacokinetics 1,
What two main processes determine...,
What are the two major types of t...
32
cards
L3: Drug absorption
What are the different routes of ...,
What determines drug absorption f...,
What are the main factors affecti...
25
cards
L4: Drug absorption
Blank 1,
Why are there alternative injecti...,
What are the main advantages of i...
34
cards
L5: Drug formulation
What is pharmaceutical availabili...,
What physical formulation factors...,
What is an excipient and give an ...
30
cards
L6: Drug Distribution
What is drug distribution 1,
What are the 4 main factors affec...,
How does blood flow affect distri...
16
cards
L7: General principles of drug metabolism
What is xenobiotic metabolism 1,
What is the aim of xenobiotic met...,
What are the sites of metabolism 3
36
cards
L8: CYP450 enzymes
What is the main function of cyto...,
Where are cyp450 enzymes mainly f...,
What gives cyp450 enzymes their n...
35
cards
L9: CYP450
Where are cyp450 isoforms encoded 1,
What is a key property of cyp450 ...,
Why is identifying the cyp450 tha...
44
cards
L10 – non-P450 mediaed phase I metabolism
What are the two main types of no...,
Name the non p450 enzymes involve...,
Name the non p450 enzymes involve...
43
cards
L11: Phase II Metabolism
What is the primary aim of phase ...,
What is the usual outcome of phas...,
Do phase i and phase ii reactions...
42
cards
L12: Phase II metabolism
What types of groups are acetylat...,
Which enzyme and cofactor are inv...,
Where does acetylation occur with...
39
cards
Lecture 13: Enzyme Induction in Drug Metabolism
How were cytochrome p450 enzymes ...,
What happens when a drug induces ...,
Which drug is a classic cyp induc...
25
cards
Lecture 14: Enzyme Inhibition & Its Importance in Drug Metabolism
What is the effect of enzyme inhi...,
Why is enzyme inhibition clinical...,
What is the role of cyp450 in dru...
32
cards
L15: Physiological & Pathological Factors Affecting Xenobiotic Metabolism
What is a key limitation in drug ...,
What is bilirubin and how is it n...,
Why are neonates susceptible to k...
36
cards
L16+17 Pharmacogenetics & Drug Metabolism
What is pharmacogenetics 1,
What types of genetic polymorphis...,
How frequently do polymorphisms o...
43
cards
L18+19: Renal excretion (rerevise)
What are the features of the filt...,
Describe the structure of podocyt...,
What are the only two things the ...
101
cards
L20 - The role of the transporters in pharmacokinetics
What are the 3 key factors that i...,
What roles do drug transporters p...,
Name the two main transporter fam...
40
cards
L21+22: PK
What are the problems in dosing d...,
What factors affect drug effects 2,
What is the order of drug process...
108
cards
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PED2001
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