This class was created by Brainscape user Mehmet Hazirci. Visit their profile to learn more about the creator.

Decks in this class (14)

Pharmacodynamics
Define "drug" and "drug target site" List the 4 main categories of drug target site Explain specificity and its relation to structure activity relationships Explain the link between drug dosage and effect, relating it to toxicity Explain how affinity and efficacy relate to the drug-receptor interaction Differentiate full and partial agonists Interpret log-dose response curves to a specific agonist in the presence of a competitive antagonist and an irreversible antagonist and explain the differen
22  cards
Pharmacokinetics
List major routes by which drugs are administered & give advantages and disadvantages Identify factors that affect drug passage across membranes determining drug distribution Identify the routes and biochemistry of Phase 1 and Phase 2 metabolism Explain how drug action can be terminated, and identify the principal routes routes of drug metabolism & excretion Define: first-pass metabolism, enterohepatic circulation, drug half-life, apparent volume of distribution, bioavailability, drug clearance.
28  cards
Pharmacokinetics of Alcohol and Cannabis
Predict how lipid solubility of alcohol and cannabis will influence distribution Calculate amount of alcohol administered within specific doses and predict likely bioavailability for each dose Compare and contrast how alcohol and cannabis are absorbed and distributed throughout the body Compare and contrast alcohol and cannabis metabolism and evaluate how active metabolites contribute to drug effect
18  cards
How Cannabis and Alcohol Induce a Depressant Effect
Identify potential drug targets for alcohol & cannabis and discuss the difficulties associated with predicting these drugs' effect on the brain Evaluate how the major toxic effects associated with alcohol & cannabis are produced and discuss the comparative toxicity of the two drugs
9  cards
Predicting how Pharmacokinetic Drug Profiles Relate to Addictive Potential
Predict how administrative route of cocaine and nicotine influences the speed of onset of CNS effects Explain how the metabolism of cocaine and nicotine contribute to their addictive potential
4  cards
Comparing and Contrasting the Drug Targets for Cocaine and Nicotine
Explain how cocaine can influence catecholamine reuptake proteins & establish changes in drug receptor interactions Utilise HH equation to predict localisation of cocaine at lipid membranes and explain how this relates to local anaesthetic effects Identify nicotine's drug target and distinguish between its autonomic and somatic NS actions Compare and contrast the stimulating ability of cocaine and nicotine Compare and contrast the cardiovascular toxicity of cocaine and nicotine
9  cards
The Importance of Modifying Opiod Structure to Enhance the Activity of These Drugs Within The Body
No deck description has yet been added by the author.
9  cards
The Mechanism for the Major Therapeutic and Toxic Effects of Opioids
No deck description has yet been added by the author.
16  cards
Key Biochemical Aspects of Obesity
No deck description has yet been added by the author.
7  cards
Anti-Obesity Agents
No deck description has yet been added by the author.
5  cards
Microbes in Health and Disease
No deck description has yet been added by the author.
16  cards
Antimicrobial Resistance
No deck description has yet been added by the author.
5  cards
Cancer Chemotherapy
No deck description has yet been added by the author.
7  cards
Anticancer Chemotherapeutic Agents
No deck description has yet been added by the author.
17  cards

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pharmacology and toxicology

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