Anti-virals Flashcards
1
Q
All of the -cyclovirs do what?
A
Competitively inhibit DNA polymerase, compete with deoxygunosine triphosphatefor entry into viral DNA
2
Q
Acyclovir used to treat
A
VZV
3
Q
Acyclocir
A
seizures. acyclovir makes you psycho
4
Q
Famciclovir
A
VZV and HHV-8 (latent)valacyclovir
5
Q
AE of famciclovir
A
Can cuase nephrotoxicity.
6
Q
Ganciclovir treats
A
HHV 6 and 8 (active)
7
Q
AE of Ganciclovir
A
Teratogenic and myelosuppresive
8
Q
valacyclovir
A
pro-drug, treats VZV and HHV-8 Latent
9
Q
Valgancyclovir
A
HHV6 and 8 latent. myelosuppresive and t4eratogenic
10
Q
CIDFOVIR
A
this is a non-cyclovir and the non-cyclovirs are not reliant on intracellular kinase phosphorylation as a prerequisite for activity so they…ARE ACTIVE AGINST KINASE deficient strains
Pox family and hhv 6,7,8
11
Q
foscarnet
A
hhv 6
