Skin

Question 1

Stratum basale

Answer 1

Cuboidal or columnar

Hemidesmosomes

Mitotic figures

Contains melanocytes (MITF disease: regulates differentiation of melanocytes. Lack of MITF=ocular albinism type 1. Excess MITF=melanoma)

Question 2

Stratum spinosum

Answer 2

Lots of desmosomes

Prickle cells

Question 3

Stratum granulosum

Answer 3

Increased lamellar bodies and tight junctions

Question 4

Stratum lucidum

Answer 4

Barrier to water

Question 5

Stratum corneum

Answer 5

Aids in permeability barrier

Keratin filaments

Question 6

Outside of mouth is keratinized and inside is NOT keratinized

Answer 6

True

Question 7

Skin exposed to UV radiation, more melanin is sent to surface of skin, it absorbs UV and as more accumulates the skin tans

Sunburn=when skin can’t make melanin fast enough to prevent UV damage to blood vessels

Answer 7

True

Question 8

Filaggrin

Answer 8

Loss of function leads to dry, scaly skin (ichthyosis vulgaris)

Question 9

Merkel cells

Answer 9

Resemble keratinocytes