Lasers in Plastic Surgery Flashcards

1
Q

What does laser stand for and how is it different from other forms of light?

A

Light

Amplication by

Stimulated

Emission of

Radiation

Lasers are more organized, monochromatic, (CCHI)

  • Collimated (travels in a collimated beam - parallel)
  • coherent (travels synchronously)
  • homogeneous (form the same source/monochromatic) - Intense
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2
Q

What is the wavelength of UV, visible and IR light

A
  • UV 100-400nm
  • Visible 380-700
  • IR 780-3000
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3
Q

What is the difference between ablative and non-ablative lasers

A

* vaporization of epidermis and superficial dermal coagulation:

  • Ablative (neodynium-YAG, CO2) produces
    • vaporization of the epidermis
    • coagulation of the dermis with surrounding thermal damage
    • => resulting in collagen remodelling, tightening skin, reversing actinic changes
  • Non-ablative laser
    • no vaporization of epidermis - protect epidermis by cooling during treatment
      • eg. thermage - monopolar radiofrequency with simutaenous cryogenic cooling
    • does coagulate deeper dermis with collagen remodelling
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4
Q

What is a chromophore

A
  • substance in tissue capable of absorbing light
  • chormophores absorb light and convert to thermal energy
  • Eg of chromophore (substances that can absorb light)=
    • Hb, OxyHb
    • betacarotene
    • collagen in dermis
    • melanin
    • water
    • tattoo ink
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5
Q

What are clinical applications of lasers

A
  • skin resurfacing
  • scarring
  • tattoo
  • acne
  • hair removal
  • benign skin lesions: pigmented/nonpigmented/vascular
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6
Q

What contraindications to laser use

A

Absolute

  • active bacterial/viral infection
  • Isotretinoin (Accutane) use in last 1-2yrs
  • ectropion

Relative

  • CVD
  • hx of keloid/HTS
  • hx of radiation at site for laser
  • ongoing UV exposure

Caution

  • smokers
  • dark skinned individual
  • neck resurfacing
  • hs of chemical peel, dermabrasion, laser
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7
Q

What lasers are used for Vascular lesions (targeting OxyHb, Hb)

A

Lasers

o Potassium titanyl phosphate (KTP) 532 nm

o Yellow pulsed dye 585 or 600 nm

o Alexandrite 755 nm

o Diode 800, 810, 940, 980 nm

o Neodymium:yttrium-aluminum-garnet (Nd:YAG) 1064 nm

Lesions

o Hemangioma – Nd-YAG (contraindicated in proliferative stage)

o Capillary malformation (post-wine stain) – pulsed yellow dye

o Venous & venolymphatic malformations – Nd-YAG (done with surgical debulking or sclerotherapy)

o Facial telangiectasia & rosacea – KTP > pulsed yellow dye > diode > Nd:YAG

o Spider veins – Nd:YAG >KTP, pulsed dye (address venous insufficiency as well)

o Kaposi’s sarcoma – pulsed dye (585nm) – less scarring but required repeated treatment q4 weeks

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8
Q

What pigmented lesions are treated with lasers (targets melanin)

A

o Lentigines

o Seborrheic keratoses

o Ephelides (freckles)

o Café-au-lait macules (High recurrence rate)

o Becker’s nevus (Brown irregular patch with dark, coarse hair)

  • Q-switched ruby slightly more effective for pigment, but long pulsed lasers better for hair removal

o Melasma (caution with treatment, may worsen and recurrence common)

o Congenital nevi (Controversial, creates difficulty in surveillance for malignant transformation)

o Nevus of Ota: Blue-black, brown, or grey patch in trigeminal nerve distribution. Nevus of Ito: Blue-black, brown, or grey patch on shoulder

Lasers are Q-swtiched (pulsed to shorter duration)b/c longer wavelength than what is needed for absoption of visible light (melanin)

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9
Q

How do lasers treat tattoo

?

A

Laser fragments the pigment and macrophages phagocytyse the pigment

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10
Q

What lasers are used for which color pigment of a tattoo?

A
  • Dark ink (black, blue) – Nd:YAG 1064nm (although many will work)
  • Green ink: Q-switched alexandrite
  • Red inks (purple, red, brown): frequency doubled Q-switched Nd:YAG (KTP) 532 nm
  • Yellow and orange ink highly resistant to treatment
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11
Q

What lasers are used for scarring (target OxyHgb)

A
  • HTS/keloid/burn:
    • Pulsed Dye 585/595
    • freqeuncy doubled NdYAG 532 (KTP)
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12
Q

What lasers are used for skin resurfacing (target H20) and how do they effect the skin

A
  • CO2
  • Er:YAG
  • IPL

Effects

  • can reach upper reticular dermis ->stimulate angiogenesis, neocollagenf ormation, elastic fiber formation
  • less hypopigmentation as melanocytes retain function
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13
Q

Which laser are used for hair removal and what is the optimal peri-operative treatemnt/preparation

A
  • seletive photolysis of the bulb
  • Q-switched ruvy or alexandrite
  • Peri-operative prep
    • hydroxyquinone pretreatment
    • Hair in anagen phase (to increase melanin relative to skin)
    • no hair removal for 1mth before
    • no sun exposure 4wks before
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14
Q

What are commonly used lasers, their uses and wavelengths

A
  • Pulsed Dye = 585
  • Qswitched Ruby = 694
  • Alexandrite = 755
  • Q-switched Nd-YAG = 1064/532
  • Erbium = 2940
  • Carbon dioxide = 10600
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15
Q

What is the pulse width, wavelength and spot size

A
  • All factors determing the depth of penetration
  • Pulse width: DURATION of exposure
    • the larger the Pw, the greater the penetration
  • Wavelength: distance between peaks
    • the longer the wavelength, the deeper
  • Spot size: area over which the laser is distribtued
    • the larger the spot size, the deeper b/c less scatter
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16
Q

What is thermal relaxation time and selective photothermolysis

A
  • Thermal relaxation - time it takes for cell to cool off by 50% after laser pulse exposure.
    • if Tr is shorter than duraiton of laser pulse, will get spill over of laser E to other cells and collateral damage. Want long Tr or short laser pulse time
  • Selective photothermolysis
    • targeted absorption of laser E by particular chormophores in select tissues to limit thermal E delivery to particular tissue
17
Q

What is the mechanism of action of Q-switched Nd-YAG = 1064/532

A

fragmentation of intracellular targeted pigment whcih is then cleared by phagocytosis

The Q-switched (quality) means the skin is exposed to lase rpulse for 20 and 50ns = very short exposure time relative to Thermal relaxation of the cell = resulting in less collateral damage

18
Q

Why is consideration fo fitzpatrick classification so important for the application of lasers

A

Pigmentary changes post laser is most common complications = Fitzpatrcik 4-6 - darker skin types - complication is more common

19
Q

What is the mechanism of action of CO2 laser in skin resurfacing

A
  • targets water
  • causes vaporization of target cell and denaturaion of extracellular protein
  • get removal of epidermis and part of dermis - depending on energy delivered
    • get smoothening of rhytids but secondary erythema, edema, pigmentary changes
  • Erbium:YAG laser also targets H20 but with higher affinity than CO2
    • = less thermal collateral damage but also less effect on rhytids
20
Q

Describe your perioperative care of patient undergoing Laser treatment

A
  • Sunscreen/protection 1yr pre and post laser
  • Topical Retinoic acid (0.025-0.01%) daily 8wks
  • Topical vit C for 2-8wks
  • topical hydroquinone (2-4% BID) for 8wks
  • HSV prophylaxis
    • Hx: Valtrex 500mg BID x3days pre, 10d post
    • no Hx: Valtrex post only 10d

INTRA-op

  • OCular protection : teatracaine and metal shields
  • Anesthesia - EMLA/local/GA/sedation
  • closed systems for O2 delivery
  • Skin: moist towels in site, teeth protection
  • skin prep non flammable

POST-op

  • Abx (clox,cipro x14days)
    • fluconazole 400mg x1 if hx yeast infx
    • steroid
  • Dressing: no poly
    • Closed - opsite - moist, less pain but can trap bacteria
    • Open - soaks intermittent w 0.025% acetic acid, lots of vaseline and ice pack
21
Q

What are complications of laser treatment

A
  • PIGMENT
    • Hyper: 1/3 of people 6wk-6m post T in Fitz 3/4 if no hydroquinone preTx. Due to upward melnoacyte migration
      • Rx: topical hydroquinone/cortison, tretinoin, vitc&E
    • Hypo: 6-24mths later in Fitx 1-3
      • Rx: tretinoin
  • WOUND HEALING
    • ​Swelling and Erythema - 100% - last 6wks to 6m
      • Rx: hydrocortisone topical after re-epi
    • Pruritus: common wk 2
      • Rx antihistamines
    • Scarring
    • Ectropion
  • PHOTOSENSITIVITY
  • INFECTION
    • HSV - Tzank smear - Valtrax 1000mg tid
    • Candida - KOH slide - fluconzaone 200 daily
    • pseudomonas - cipro 500 bid
  • ACNE AND MILIA
    • parallels thermal injury +/- occlusve dressing/vaseline
      • Rx: tretinoin+ tetracyline
  • CONTACT DERMATITIS
    • ​occurs because direct contact w langerhans cells - makeup/topical antimicrobial
      • ​rx: d/c topical
22
Q

What is intense Pulsed light and how does it differ from laser light

Indications and contraindications

A
  • non-coherent
  • polychromatic
  • 510-1200nm
    • targets water Hb 550-580
    • superficial pigment 550-570 - melanin, Oxyhb
    • darker pigment 590-775
  • filters are used to incl/excl particular Wavel

Used for treatment of

  • hyperpigmentation (solar lentigines, melasma, freckling)
  • hypervascularity (telangiectasia, rosacea, flushing)
  • hair reduction
  • improvement in skin texture and decrease pore size

Pre-treatment not necessary, expect only 24hrs of redness

Contraindications

  • wound healing
  • photosensitizing agets
  • active accutane treatment
  • skin cancer
  • fitz 6
23
Q
A