Gynecologic Oncology Flashcards
Type of hydatidiform mole that is positive for p57Kip2 immunostaining
Partial mole
Paternal age is a risk factor for this type of hydatidiform mole
Complete mole
Beyond this age, the risk of acquiring a hydatidiform mole is increased ten-fold
40 years
Sonographic sign of complete hydatidiform mole on pelvic ultrasound in the second trimester
Snowstorm-like appearance
Drug of choice in chemoprophylaxis for malignant degeneration of hydatidiform moles
Methotrexate
Preferred contraceptive method after a molar pregnancy
Low dose oral contraceptive pills
A rare neoplastic proliferation of intermediate trophoblasts that invade the myometrium at the placental site after a pregnancy
Placental site trophoblastic tumor
A rare trophoblastic neoplasm which is the malignant counterpart of intermediate trophoblasts of the chorion leave
Epithelioid trophoblastic tumor
A tumor or tumor-like process invading the myometrium and characterized by trophoblastic hyperplasia and persistence of placental villous structures
Invasive mole
An epithelial malignancy of trophoblastic cells formed by the abnormal proliferation of cytotrophoblasts and syncytiotrophoblasts in the absence of chorionic villi
Choriocarcinoma
According to the 2000 FIGO Anatomic Staging, a gestational trophoblastic neoplasia with metastases only to the lungs are assigned as:
Stage III
Karyotypes of partial hydatidiform moles
69,XXX
69,XXY (more common)
[Multiparity / Nulliparity] triples relative risk of acquiring endometrial cancer.
Nulliparity
A histopathologic finding that is described as a single papilla lined by tumor cells and contains a central vessel. This is pathognomonic of yolk sac tumors.
Schiller-Duval body
A complete hydatidiform mole has a [lower / higher] chance of malignanr sequelae than partial moles
Higher (15%, compared to 4-6% for partial moles)
