Pathology Flashcards

1
Q

What are the common causes of lobar pneumonia?

A

streptococcus pneumoniae
Klebsiella
Legionella

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2
Q

Two clinical settings of pneumonia

A

Community acquired

Hospital Acquired

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3
Q

Two forms of clinical pneumonia

A

Lobar

Broncho

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4
Q

What cells and structures might you see in the pathology of a lobar pneumonia? (3)

A

Neutrophils
Macrophages
Fibrin rich exudate

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5
Q

What are common complications of lobar pneumonia?

A

Fibrous scarring
Abscess formation
Bronchiectasis
Empyema

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6
Q

Bronchopneumonia is more commonly seen in otherwise healthy young adults - True or False

A

False

Bronchonpneumonia is normally seen in the context of pre-existing disease

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7
Q

Bronchopneumonia is commonly a result of aspiration - True or False?

A

True

This leads to more anaerobic and staphylococcal infections rather than streptococcal

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8
Q

Most common complication of bronchopneumonia

A

Abcscesses

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9
Q

Common symptoms of an abscess (3)

A

chronic malaise
fever
weight-loss

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10
Q

Diseases commonly associated with bronchiectasis (3)

A

TB
CF
Pneumonia

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11
Q

Why are bronchiectasis patients more prone to infection?

A

the dilated airways accumulate purulent secretions causing infective pus formation

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12
Q

The pathology of TB is mediates by a ______ hypersensitivity reaction

A

Type IV

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13
Q

Primary TB is…

A

1st exposure and up too 5 years after

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14
Q

Where can a granulomatous response be seen in the lungs with TB?

A

In the hilar lymph nodes

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15
Q

Secondary TB is…

A

the 2nd exposure causing reinfection or reactivation of disease

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16
Q

Where does TB typically localise?

A

apices of the lungs

17
Q

Where would a Ghon focus be found?

A

periphery of mid zone of lung

18
Q

TB reactivation can result due to decreased T cell function. What may be the reason for this?

A

Age
Coincident disease (HIV)
Immunosuppressive therapy

19
Q

What is the common viral infection of an immunocompromised host?

A

cytomegalovirus

20
Q

What are the common fungal pathogens in the immunocompromised host?

A

aspergillus, candida, pneumocystis