Mood Disorders Flashcards
By the numbers
Major depression more in women
Bipolar is equal
MD leading cause of disability ages 15-44
Development of MD
HC, Limbic, amygdala, anterior cingulate, hypothalamic pituitary
Complex interactions between regions and NTs coupled with genetics and environmental factors lead to development
MD and suicide
Most contemplate
10-15% die
Major depression guidelines
5 of following symptoms during same 2 week period and represent change…at least 1 is either depressed moodd or loss of interest/pleasure
Depressed mood most of day everyday
Markedly dmiinished interest in all or almost all activities nearly everyday
Weight loss when not dieting or decrease appetite
Insomnia or hypersomnia
Psychomotor agitation/retardation
Fatigure/loss of energy
Feeling or worthlessness or guilt
Diminished ability to think or concentrate/indecisiveness
Recurrent throughts of death/suicidal plan
Other MD requirments
Symptoms cause clinically significant distress or impairment
Episdoe not attributable to substnace or other condition
Occurrence is not better explained by another mental disorder
Never been manic or hypomanic episode
Anxious distress
Mixed features
Seasonal pattern
Feeling tense/restless/difficulty conentrating and fear something awful may happen
Manic/hypomanic symptoms present nearly every day during episode
Regular relationship between onset and time or year
Melancholic
Atypica
Peri-partum
Loss of pleasure Profound despondency, despair. Worse in morning and early morning wakening Psychomotor agitation/reatardation Guilt
Modd reactivity/weight gain or increase in appetite/hypersomnia/leaden paralysis
During pregnancy or in 4 week following…emergency
Grief vs MD
Grief - empitness and loss
MD - presistent depressed mood and inability to anticipate happniess and pleasure
Dysphoria in grief will decrease
Grief thoughts normally associated with lost loved one
PDD
Depressed mood for most of the day for more days than not as indicated by subjective account for at least 2 years
2 or more of following poor appitaite or overeating Insomnia/hypersomnia Low energy Low self-esteem Poor concentration or decision making Hopelessness
Symptoms not from drugs or other
CSI
Dysthymia (persistent) vs. major depression
Dysthymia - 2 weeks, depressed plus 2 others, more cognitive symptoms, mild onset may be followed by major after 2 years
MD - 2 weeks, depressed plus 5 other sx, more vegetative sx, more severe symptoms
Manic episode
Lasting at least one week
3 of following during increased mood and energy Inflated self-esteem/grandiosity Decreased need for sleep More talkataive Flighjt of ideas Distractibility Increase goal-directed/pschomotor agitation Excessive risky behaviors
Mood disturbance causes CSI or hospitalization
Not from drugs
Hypomanic episode
4 days
Same symptoms (3 of them)
Associated iwht change in functioning that is uncharactersitic
Disturbance is observable
Episode NOT severe neough to cause CSI or hospitalization
Not a drug
Bipolar 1 v.s 2
1 - one or more manic episodes
2 - one or more hypomanic episodes but there has never been a manic…presence of one or major MD episodes
Cyclothymic disorders
For at least 2 years, numerous periods iwth hypomanic symptoms that do not meet criteria for hypomanic episode and numerous with depressive that don’t meet MD
Hypoamnic and depressive periods present for at least 1/2 the time and not been w/out symptoms for more than 2 months
Cause CSI
Not drug
Substance use disorders
Prevalence of depression higher in active drinkers
Important to ID which came first
