BC Pelvic Mass Flashcards

1
Q

Tumour markers for pelvic masses?

A

hCG, AFP, LDH, Ca125, Ca19-9,

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2
Q

What is hCG positive associated with in regards to tumour marking?

A

Embryonal cell carcinoma, ovarian choriocarcinoma, mixed germ cell tumours, dysgerminomas

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3
Q

What does AFP mark for (tumour markers in pelvic masses)

A

Yolk sac tumours** (some immature teratomas)

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4
Q

DO dysgerminomas have a normal AFP or high?

A

NORMAL

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5
Q

What does LDH mark for as a tumour marker for pelvic mass?

A

dysgerminomas

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6
Q

What does Ca125 mark for ?

A

nothing specific just elevated with cancer

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7
Q

What does Ca 19-9 mark for?

A

pancreatic ca, can also see with some ovarian tumours

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8
Q

What is a krukenburg tumour?

A

occurs in GI tract but has mets to the ovaries

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9
Q

What do signet ring cells signify?

A

krukenburg tumour (from GI tract)

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10
Q

Which of the following statements about ovarian teratomas are false?

a) They are also called dermoid cysts
b) They most commonly affect women in their reproductive years
c) They extremely rarely undergo malignant degeneration
d) They are bilateral in 10% to 15% of cases
e) All of the above statements are true

A

All of the above

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11
Q

A 66 year old woman presents with a 3 month history of fatigue, anorexia, nausea, weight loss and vague abdominal pain. Her waistline has increased during that time and she says she now requires a larger dress size. On exam, ascites and a left ovarian cyst measuring 8 cm in diameter are noted.
Ultrasound shows the cyst as having septations, the uterus as small and the right ovary not visualized. Ca 125 level is 100.

Which of the following is the best provisional diagnosis?

a) Carcinoma of the fallopian tube
b) Carcinoma of the ovary
c) Cystadenoma of the ovary
d) Carcinoma of the pancreas with pelvic metastasis
e) Krukenberg tumour

A

ca of ovary

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12
Q

If cyst <6cm what do you do?

A

follow up 6wk later

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13
Q

What is the most common benign neoplasia of the ovary?

A

dermoid cyst

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14
Q

Patient over 40 with ovarian Ca, what kind of ca is it?

A

epithelial cell

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15
Q

What is the most common type of ovarian Ca in patient <20yo

A

Germ cell

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16
Q

What age group is germ cell ovarian ca most common?

A

<20yo

17
Q

What age group is epithelial cell ca most common in?

A

> 40yo

18
Q

What are the risk factors for endometrial Ca?

A

increasing age, unopposed estrogen, tamoxifen, early menarche, late menopause, nulliparity, PCOS, obesity, DM, estrogen secreting tumour, lynch syndrome, cowmen syndrome, family hx of endometrial, breast, colon

19
Q

what is the management for endometrial ca?

A

hysterectomy, bilateral salpingo-oophorectomy