Obesity and Nutrition Flashcards
What is orlistat?
A lipase inhibitor used for weight loss
What is the process by which orlistat functions?
Prevents breakdown of dietary fat
What is the main side effect of orlistat?
Steatorrhoea
At which BMI(s) can orlistat be indicated for use?
- >30
- >28 (with comorbidities)
In which instances is orlistat contraindicated?
- Malabsorption
- Breastfeeding
- Pregnancy
- Reduced gallbladder function
Absorption of what is inhibited when taken orlistat?
- Fats
- Fat soluable vitamins (A, D, E, K and beta carotene)
What are the main drug interactions associated with orlistat?
- Ciclosporin
- Amiodarone
- HIV antiretroviral medications
Which medication does not interact with orlistat, yet must have its dose lowered when taken in conjunction with orlistat?
Warfarin
Vitamin K (a fat soluable vitamin) is not absorbed as well which depletes blood clotting capacity enhancing the effect of warfarin
Orlistat is incredible useful at preventing the onset of which condition?
Type 2 diabetes
Orlistat is safe for use for how many years?
4
What defines a very low caorie diet (VLCD)?
<800Kcal but >450Kcal
What are some key side effects to following a VLCD?
- Gout
- Gallstones
- Cramps
- Dizziness
- Constipation or diarrhoea
At which BMI(s) is bariatric surgery indicated?
- >40
- >35 (with comorbidities)
What are the two types of bariatric surgery?
- Restrictive (changes stomach capacity)
- Malabsorptive (bypasses portions of the small intestine)
Bariatric surgery commonly involves aspects of both
For which anatomical reason may a gastric band decrease apetitite?
Compresses vagus nerve
