antepartum and postpartum hemorrhage Flashcards

1
Q

antepartum hemorrhage definition

A

20+ weeks bleeding

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2
Q

differential diagnosis for antepartum hemorrhage

A

abruption
placenta previa

vasa previa
labour
lower genital tract lesion
uterine rupture
unclassified /  marginal separation
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3
Q

management/workup of antepartum hemorrhage

A

vitals / stability
fetal heart rate monitor + toco

if unstable, stabilize +/- deliver

hx - FM, amount, ctxns, ROM, pain, other
US for placental location
spec exam - lesions, ROM, bleeding amount + location VE - ONLY after US to r/o previa: cervix

CBC, group + screen, coags, Betker-Kleinhaur test

Rh if indicated

admit for monitoring for 48hrs if had significant bleed

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4
Q

placenta previa definitions

A

complete: covers os
central: int os equidistant from ant + post edge
partial: covers part
marginal: adjacent but doesn’t cover

low lying: within 2 cm

can do TOL if >10mm

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5
Q

diagnosis of placenta previa

A

TVUS

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6
Q

RFs for placenta accreta

A
prior placenta previa
prior CS or surgery
multiples
multiparity
AMA
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7
Q

asymptomatic placenta previa management

A
  • if <2cm at anatomy scan, repeat at 32-32wks
  • avoid intercourse, exercise, seek attention if ctxn or bleed
  • C/S at 37-38wks
  • cross match and type blood at delivery
  • can use tranexamic acid if need at delivery
  • can use cell saver to return blood
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8
Q

management of bleed in previa

A
  • painless vag bleed
  • admit + start maternal + fetal monitoring
  • ABCs
  • give IV crystalloids
  • take blood: CBC, coags, group and screen, cross match and type 4 units RBCs
  • O2 and pulse oximetry

if mom or fetus unstable

  • stablize
  • transfuse, watch for DIC
  • call code OB
  • immediate CS

both stable:

  • mature fetus: CS
  • immature: steroids, transfusion, transfer, monitor, can discharge if no bleed for 48 hrs + outpatient monitor

Rhogam if indicated

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9
Q

abruptio placenta causes

A
  • chronic vasculopathy, thromboses, failed transformation
  • trauma
  • PPROM
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10
Q

RF for abruption

A
prev hx
trauma
ROM
fibroid
uterine or placental anomaly
smoking
HTN
parity
AMA
cocaine
thrombophilias
multiples
polyhydramnios
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11
Q

symptoms + signs + labs of abruption

A
  • vag bleed
  • abdo pain
  • contractions
  • FHR abnormality/demise
  • back pain
  • US may be normal
  • coagulopathy: hypofibrinoginemia and thrombocytopenia

note: concealed hemorrhage or couvelaire uterus is possible

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12
Q

management of abruption

A
  • determine stability of mom + baby
  • 2 large bore IV, crystalloids
  • blood: CBC, coags, G + S, cross + type
  • cont monitoring
  • O2 + pulse oximetry

if unstable:

  • call for help
  • rescus/stabilize
  • deliver
  • watch for DIC

if stable:

  • mature: vag delivery or CS
  • immature: steroids, transfuse, transfer, admit for monitoring, induce when term
  • if dead fetus: induce labour + watch for DIC

Give Rh if indicated + Betke Kleihauer test

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13
Q

vasa previa description + management

A
  • fetal vessels transverse membranes ahead of presenting part
  • usually /w velementous cord insertion (naked vessels in membranes)
  • rupture –> sinusoidal heart rate, fetal hypotension + anemia
  • mild vag bleeding
  • high fetal mortality
  • emergency CS
  • rare can dx on VE or US
  • fetal surveillance + cervical length, schedule CS at maturity
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14
Q

defintion of PPH, immed, delayed

A

> 500cc in VD
1000cc in CS

immed = within 24 hrs
delayed = 24hrs - 6 wks
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15
Q

causes of PPH

A

Tone - atony, multiples, macrosomia, precipitous or long, polyhydraminos, oxytocin, GA, grand multip, infection (fever, prolonged ROM), fibroids, previa

Trauma - uterine, cervical or vac laceration, uterine rupture or inversion

Tissue - RPOC, abnormal placentation, retained clot

Thrombin- coagulopathy (hemophilia, VWD), acquired (ITP, thrombocytopenia /w pre-eclampsia, DIC), anticoagulants

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16
Q

prevention of PPH

A
  • oxytocin after delivery
  • clamp + cut cord
  • palpate fundus, firm
  • gental cord traction + counter traction - avoid inversion
  • oxytocin infusion if placenta not delivered in 15 min
  • palpate fundus after placenta
  • inspect placenta
  • examine genitalia for lac, hematoma
17
Q

management of PPH

A
  • ABC: vitals, large bore IV, crystalloids wide open
  • CBC, cross match and PT/PTT, fibrinogen levels
  • call help, notify blood bank possible MTP
  • assess fundus, if boggy bimanual massage
  • explore cavity for retained products, inversion, or rupture if analgesia permits
  • look for genital lesions, placenta complete
  • empty bladder + monitor urine output
  • may need to examine under anaesthesia

drugs

  • oxytocin: 5 units IV bolus, 20-40 units/250ml crystalloid, 10 units IM if no IV
  • carbetocin: 100ug IV/IM
  • hemabate: 250ug IM or intramyometrial, repeat q15min PRN up to 2mg - CI if asthma
  • methylergonovine maleate: 0.25mg IM/0.125mg IV, q5min up to 5x - CI in HTN
  • misoprostol: 600-800ug SL or PR, SE = pyrexia
  • tranexamic acid: 1g IV

procedures

  • bakri balloon
  • uterine vessel ligation
  • internal iliac artery ligation
  • uterine suturing techniques
  • hysterctomy

If coagulopathy

  • FFP
  • cyroprecipitate
  • platelets
  • RBCs
18
Q

RF/causes of inversion

A

iatrogenic often

grand multip /w fundal placenta

19
Q

diagnosis + effects + tx of inversion

A

placenta at introitus /w mass attached

shock: bradycardia from vagal tone

replace uterus promptly /w placenta

NO (tocolytic) may help replace

if fails laparotomy