8 steps

Question 1

Transcription

Answer 1

Thalassemias and hereditary persistence of fetal hemoglobin

Question 2

Translation

Answer 2

Thalassemias

Question 3

Polypeptide folding

Answer 3

hemoglobinopathies

Question 4

post-translational modification

Answer 4

I-cell disease (failure to add a phosphate group)

Question 5

assembly of monomers into a holomeric protein

Answer 5

osteogenesis imperfecta

Question 6

subcellular localization of the polypeptide of the holomer

Answer 6

familial hypercholesterolemia

Question 7

cofactor or prosthetic group binding to the polypeptide

Answer 7

homocystinuria

Question 8

function of a correctly folded, assembled and localized protein produced in normal amounts

Answer 8

Hb Kempsey