What is the difference between arthritis and spondyloarthritis?
Spondyloarthritis affects the joint, tendon/ligament AND the enthesis (where the tendon/ligament attaches to the bone)
What are the four types of arthritis covered by the term by spondyloarthritis?
Which gene mutation predisposes you to develop spondyloarthritis?
Which joints tend to be involved in spondyloarthritis?
Describe mechanical and inflammatory joint pain.
Mechanical pain - worse during activity, better at rest, worst at the end of the day
Inflammatory - worse with rest, better with activity, worst in the morning and lasts > 30 mins
Which joints are affected in all spondyloarthropathies?
+ Upper and lower limb joints
Name an enthesis which is commonly affected by spondyloarthritis.
Achilles tendon enthesis
What is dactylitis?
What does it look like?
Inflammation of an entire digit
What is the most common spondyloarthritis which primarily affects the spine?
What is the main symptom of ankylosing spondylitis?
What are some extra-articular features of ankylosing spondylitis?
Aortic valve disease
What are syndesmophytes?
Intervertebral discs fuse with bone, making spinal joints less mobile
How is ankylosing spondylitis treated?
Physio / OT
Which derm condition has an arthritis associated with it?
What nail pathology is seen in psoriatic arthritis?
Are patients with psoriatic arthritis positive for rheumatoid factor?
RF isn't raised in psoriatic arthritis
What is the difference between septic arthritis and reactive arthritis?
Septic arthritis caused by ongoing infection of the joint
Reactive arthritis is an autoimmune response following an general infection
How long after infection can reactive arthritis present?
1 - 4 weeks
Which infections most commonly cause reactive arthritis?
Urogenital - e.g chlamydia
Entergenic - e.g salmonella, shigella
What is Reiter's syndrome?
A form of reactive arthritis with a triad of presentations:
Ocular inflammation (conjunctivitis/uveitis/iritis)
What are the clinical features of reactive arthritis?
General inflammation symptoms (fever, fatigue, malaise)
Some people develop an arthritis associated with which GI diseases?
Inflammatory bowel disease
When does enteropathic arthritis flare up?
During flare ups of the inflammatory bowel disease
Which skin condition, associated with IBD, can also appear in enteropathic arthritis?
What drug, usually used to treat arthritis, is not a good choice for people with enteropathic arthritis?
cause GI side effects like oesophagitis and peptic ulcers
What should be given instead of NSAIDs to patients with enteropathic arthritis?
Normal analgesia - paracetamol, co-codamol
Which gene are spondyloarthopathies associated with?