9: Spondyloarthropathies Flashcards Preview

MSK Week 2 2017/18 > 9: Spondyloarthropathies > Flashcards

Flashcards in 9: Spondyloarthropathies Deck (27)
1

What is the difference between arthritis and spondyloarthritis?

Spondyloarthritis affects the joint, tendon/ligament AND the enthesis (where the tendon/ligament attaches to the bone)

2

What are the four types of arthritis covered by the term by spondyloarthritis?

Ankylosing spondylitis

Reactive arthritis

Psoriatic arthritis

Enteropathic arthritis

3

Which gene mutation predisposes you to develop spondyloarthritis?

HLA B27

4

Which joints tend to be involved in spondyloarthritis?

Spine

Usual joints

5

Describe mechanical and inflammatory joint pain.

Mechanical pain - worse during activity, better at rest, worst at the end of the day

Inflammatory - worse with rest, better with activity, worst in the morning and lasts > 30 mins

6

Which joints are affected in all spondyloarthropathies?

Spinal joints

Sacroiliac joint

+ Upper and lower limb joints

7

Name an enthesis which is commonly affected by spondyloarthritis.

Achilles tendon enthesis

8

What is dactylitis?

What does it look like?

Inflammation of an entire digit

Sausage fingers!

9

What is the most common spondyloarthritis which primarily affects the spine?

Ankylosing spondylitis

10

What is the main symptom of ankylosing spondylitis?

Back pain

11

What are some extra-articular features of ankylosing spondylitis?

Uveitis

Aortic valve disease

Pulmonary fibrosis

12

What are syndesmophytes?

Intervertebral discs fuse with bone, making spinal joints less mobile

13

How is ankylosing spondylitis treated?

Physio / OT

NSAIDs

DMARDs

Biologic agents

14

Which derm condition has an arthritis associated with it?

Psoriasis

(Psoriatic arthritis)

15

What nail pathology is seen in psoriatic arthritis?

Nail pitting

16

Are patients with psoriatic arthritis positive for rheumatoid factor?

No

RF isn't raised in psoriatic arthritis

17

What is the difference between septic arthritis and reactive arthritis?

Septic arthritis caused by ongoing infection of the joint

Reactive arthritis is an autoimmune response following an general infection

18

How long after infection can reactive arthritis present?

1 - 4 weeks

19

Which infections most commonly cause reactive arthritis?

Urogenital - e.g chlamydia

Entergenic - e.g salmonella, shigella

20

What is Reiter's syndrome?

A form of reactive arthritis with a triad of presentations:

Urethritis

Ocular inflammation (conjunctivitis/uveitis/iritis)

Arthritis

21

What are the clinical features of reactive arthritis?

General inflammation symptoms (fever, fatigue, malaise)

Asymmetrical arthritis

Mucosal lesions

22

Some people develop an arthritis associated with which GI diseases?

Inflammatory bowel disease

(Crohn's, UC)

23

When does enteropathic arthritis flare up?

During flare ups of the inflammatory bowel disease

24

Which skin condition, associated with IBD, can also appear in enteropathic arthritis?

Pyoderma gangrenosum

25

What drug, usually used to treat arthritis, is not a good choice for people with enteropathic arthritis?

NSAIDs

cause GI side effects like oesophagitis and peptic ulcers

26

What should be given instead of NSAIDs to patients with enteropathic arthritis?

Normal analgesia - paracetamol, co-codamol

27

Which gene are spondyloarthopathies associated with?

HLA B27