alzheimers

Question 1

Alzheimer med

Answer 1

1. Donepzil (aricept)
2. Rivastagmine (exelon)
3. Galantamine ( Razadyne)
4. Memantine (Namenda)
5. Namzaric ( Memantine ER+ Namenda)

Medar ar Acetylcholinesterase Inhibitor (INC Ach)

Question 2

Donepzil

Answer 2

Aricept

Indication
- Mild to moderate/ moderate to severe

Dosage form
- ODT, Tab, Patch (once weekly)
- Dose QHS

Side effect
- GI ( swallow and do not crush)

Question 3

donepzil patch

Answer 3

Adlarity

Question 4

Rivastagmine

Answer 4

**Exelon **

Indication: mild to moderate
Dosage form: Cap, Patch
Dose: BID with food (nausea)

Patch benefit
- Once daily
- less N/V

Question 5

Galantamine

Answer 5

Razadyne
- Mild to moderate
- Dosage form: (ER cap w/am meal), solution

Question 6

cholinesteras inhibitor SE

Answer 6

• Gastric acid secrettion- PUD
• N/V
• cholinergic -SLUDGE
• Bradycardia
• worsen asthma /COPD

Question 7

cholinergic agents

Answer 7

1. Bethanechol (urecholine): for urinary ret
   2. Cevimeline: for dry mouth
2. Neostigmne: for muscle strength (imp muscle strenght)
3. Physotigmine: reversal of anticholinergic toxicity

Question 8

Anticholinergic

Answer 8

OTC: benadryl
Antipsychotic drugs

Question 9

atropine (anticholinergic)

Answer 9

used for
- Symptomatic bradycardia
- inhib salivation and secretion
- Antidote for nerve agents, mushroom poison, anticholinesterase poisoning

Question 10

Memantine

Answer 10

Namenda, XR, Titration pack, titration pack XR
- MOA: NMDA receptro antagonist
- Indic: Mod- severe alzheimers
- Dosage: Ir Tab, ER caps, Sol
- SE:
-diziness (common) ,rash

Question 11

Namzirac

Answer 11

Memantine + Donepzil
inidc: Mod to severe
- take in evening

Question 12

cognitive test for Alzheimer

Answer 12

MMSE
- mini mental state examination