Anesthesia for Ophthalmic Surgery Flashcards

(94 cards)

1
Q

Presently, there are few studies available addressing postoperative complications associated with ophthalmic anesthesia. A retrospective study of prolonged postanesthesia care unit (PACU) stay following ophthalmic surgery found the incidence was about 0.6%, the most common factors being …

A

hypotension, bradycardia, postoperative nausea and vomiting (PONV), and oversedation

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2
Q

The tissue where the cornea and sclera meet is the …, which contains … responsible for …

A

limbus

stem cells

regeneration of the epithelium

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3
Q

About 60% of the focus power of the eye is from …

A

the curvature of the cornea

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4
Q

Sympathetic stimulation dilates the pupil by causing … muscles to … ,
whereas parasympathetic stimulation causes miosis, or pupillary constriction by causing the … muscles to … .

A

iris dilator

contract

iris sphincter

contract

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5
Q

The ciliary body lies just behind the iris; it produces … .

Ciliary muscle fibers adjust the focus by …

A

aqueous humor

releasing tension on the suspensory fibers, or zonules, of the lens.

  • External referene
    To focus on near objects:
    The ciliary muscle contracts. This reduces the diameter of the ring formed by the ciliary body. The tension on the suspensory zonules decreases. The lens becomes more spherical (rounder) due to its natural elasticity, which increases its refractive power.

To focus on distant objects:
The ciliary muscle relaxes. The tension on the suspensory zonules is increased. This pulls the lens into a flatter shape. The refractive power of the lens decreases, which is necessary to focus light from distant objects onto the retina.

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6
Q

The retinal layer ends approximately 4mm behind the iris. The area between the limbus of the cornea and the retina is called the … . Because there is no
retinal layer there, it is a safe entrance site for … .

A

pars plana

vitrectomy procedures

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7
Q

The center of the eye is filled with … . This thick fluid has attachments to … . Traction of the vitreous on the retina is a cause of … . Scarring, bleeding, or opacification of the vitreous is treated by … .

A

vitreous gel

blood vessels and the optic nerve

retinal detachment

vitrectomy

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8
Q

The extraocular muscles move the globe within the orbit. They arise from a fibrous ring near the apex of the orbit and insert on the … . The six extraocular muscles lie within a cone behind the eye surrounding the …

A

sclera

optic nerve, ophthalmic artery and vein, and ciliary ganglion.

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9
Q

The ophthalmic artery provides most of the blood supply to the orbital structures. It is a branch of the … , close to the circle of Willis. The … drain directly into the … .

A

internal carotid artery

superior and inferior ophthalmic veins

cavernous sinus

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10
Q

Cranial nerves (CN) innervate the ocular structures.
The … carries the neural signals from the retina.
The … nerves control the extraocular muscles.
Touch and pain sensations are carried via the… . Sensation to the lower lid is via the … . Sensation to the upper lid is via the … .
The … sends sensory fibers to the medial canthus, lacrimal sac, and ciliary ganglion

A

optic nerve (CN II)

oculomotor (CN III), trochlear (CN IV), and abducens (CN VI)

trigeminal nerve (CN V)

maxillary nerve (CN V2)

frontal branch of the ophthalmic nerve (CN V1)

nasociliary branch of the ophthalmic nerve

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11
Q

The ciliary ganglion provides sensory innervation to the… .

Parasympathetic fibers originate from the … and synapse in the … before supplying the … muscle.

A

cornea, iris, and ciliary body

oculomotor nerve (CN III)

ciliary ganglion

iris sphincter

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12
Q

Sympathetic fibers of the eye originate from the … and travel through the … to innervate the … .

A

carotid plexus

ciliary ganglion

dilator muscle of the iris

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13
Q

Local anesthetic blockade of the ciliary ganglion produces a … pupil

A

fixed, mid-dilated

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14
Q

The facial nerve (CN VII) exits the base of the skull from the … foramen. It supplies motor innervation to the … via the … branch. Local anesthetic block of the facial nerve can prevent …

A

stylomastoid

orbicularis muscle

zygomatic

lid squeezing.

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15
Q

The oculocardiac reflex was first described by … in 1908. It is also known as the … .

A

Aschner and Dagnini

trigeminovagal reflex

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16
Q

Describe the oculocardiac reflex

A

Traction on the extraocular muscles or pressure on the globe causes bradycardia, atrioventricular block, ventricular ectopy, or asystole. It is seen with traction on the medial rectus muscle, but it can occur with stimulation of any of the orbital contents, including the periosteum

The pain, pressure or traction impulses are conducted by the ciliary nerves to the
ciliary ganglion and then via the ophthalmic division of the trigeminal nerve to the Gasserian ganglion and the sensory nucleus of the trigeminal nerve. Here, the afferent limb synapses with the motor nucleus of the vagus nerve. The efferent impulses travel to the heart via the vagus nerve, leading to decreases in both heart rate and contractility of the heart.

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17
Q

The oculocardiac reflex increases with repeated stimulation

T or F

A

F

The response is minimized with repeated stimulation

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18
Q

Although the oculocardiac reflex can occur for any age group, it is more frequent in … undergoing … surgery. Premedication with … can reduce the incidence of the oculocardiac reflex, as can the choice of anesthetic agents.

A

children

strabismus

atropine or glycopyrrolate

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19
Q

Describe how different anesthetics affect the oculocardiac reflex

A

Choi et al. reported that the oculocardiac reflex was lowest in children undergoing induction of anesthesia with ketamine instead of propofol.

The use of opioids such as fentanyl, alfentanil, and remifentanil may contribute to the oculocardiac reflex.

Retrobulbar block is not uniformly effective at preventing the oculocardiac reflex. Orbital injections can also trigger the response;

hypercapnia and hypoxemia can exacerbate the oculocardiac reflex.

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20
Q

In the event of arrhythmia associated with the oculocardiac reflex, the anesthesiologist should first …

A

ask the surgeon to cease surgical stimulation

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21
Q

Management of a oculocardia reflex case that persist after the surgeon stop the surgical stimulation

A

Evaluation to determine if the patient is experiencing any condition that may exaggerate the reflex such as hypoxia, hypercapnia, or inadequate depth of anesthesia should be completed and the patient should receive immediate treatment if the rhythm disturbance persists. Treatment options include administration of intravenous glycopyrrolate 0.1–0.2 mg/(pediatric dose, 10 mcg/kg) or atropine 10–20 mcg/kg. Rarely, epinephrine may be required to treat severe bradycardia or asystole.

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22
Q

Normal intraocular pressure (IOP) is necessary to … .

Normal IOP is … and a value more than … is considered pathologic

A

maintain cornea curvature and a proper refracting index of the eye

16 ± 5mm Hg

25mmHg

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23
Q

How is the intraocular pressure regulated?

A

The globe is a relatively noncompliant compartment. The volume of the internal structures is fixed except for aqueous fluid and choroidal blood volume. The quantity of these two factors regulates IOP

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24
Q

Aqueous formation of 80% to 90% occurs through active secretion by the … mediated by … . The remainder is from … . It then enters the … to flow through the … into the … .

IOP is primarily regulated by the resistance at the …

A

ciliary body

Na-K ATPase and carbonic anhydrase enzymes

passive filtration and ultrafiltration across the ciliary epithelium

angle of the anterior chamber

trabecular meshwork

Schlemm canal and the episcleral veins

trabecular meshwork

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25
Impairment of aqueous drainage at any point can elevate the IOP. ... is believed to cause the chronic pressure elevation in open-angle glaucoma. Closed-angle glaucoma occurs when ... . This happens from peripheral iris swelling or anterior displacement. Patients with a preexisting ... may be predisposed to this condition
Sclerosis of the trabecular meshwork there is an obstruction to aqueous drainage from closure of the anterior chamber angle narrow angle
26
How do inhaled anesthetics affect the IOP?
All volatile anesthetic drugs cause a decrease in IOP. Nitrous oxide (N2O) has no effect on IOP.
27
How do induction agents affect the IOP?
The commonly used intravenous induction anesthetics such as propofol, thiopental, and etomidate all reduce IOP, with propofol causing a moderate reduction in IOP even when used as low-dose intravenous sedation. Ketamine does not increase IOP Midazolam has little effect on IOP, and sedation with midazolam has been used to facilitate the measurement of IOP in children.
28
The mechanism by which anesthetic drugs reduce IOP is not fully elucidated but involves ...
depression of central nervous system ocular centers, resulting in relaxation of extraocular muscle tone
29
How do short-acting opioids affect the IOP?
Short-acting opioids such as fentanyl, alfentanil, and remifentanil decrease IOP on induction of anesthesia
30
How do NMBAs affect the IOP?
Nondepolarizing neuromuscular blocking agents (NMBAs) such as rocuronium, vecuronium, and atracurium have little effect on IOP
31
How does succinylcholine affect the IOP?
Succinylcholine increases IOP by about 8 to 10 mm Hg due to a variety of postulated mechanisms including reduced aqueous humor outflow, increased choroidal blood volume, and increased central venous pressure
32
IOP increases after reversal of nondepolarizing NMBA with neostigmine and atropine but remains unchanged with sugammadex T or F
T
33
The most significant rise in IOP during general anesthesia occurs at ... ; the increase in IOP is even greater with repeat ... .
laryngoscopy and emergence laryngoscopy
34
Video-guided laryngoscopy causes a similar increase in IOP than direct laryngoscopy. Insertion of a laryngeal mask airway results in little or no increase in IOP. T or F
F Video-guided laryngoscopy causes a smaller increase in IOP than direct laryngoscopy. Insertion of a laryngeal mask airway results in little or no increase in IOP.
35
Other anesthetic interventions that increase IOP include ... . Coughing, straining, or vomiting can increase IOP ...
compression of the eyes during ventilation, hypoxia, hypercapnia, and hypertension 30 to 40mm Hg.
36
Ocular blocks initially decreases IOP by 5 to 10mm Hg, but this returns to baseline values within 5 minutes. T or F
F Ocular blocks initially increase IOP by 5 to 10mm Hg, but this falls to below baseline values within 5 minutes.
37
... cause the greatest increase in IOP, likely due to the greater volume of local anesthetic that is injected
Peribulbar blocks
38
Most ophthalmic drugs have negligible excretion into breastmilk, with the exception of ... eye drops, which can potentially cause adverse effects in the nursing infant
timolol
39
Acetazolamide side effects
Confusion, drowsiness, hypokalemia, hyponatremia, metabolic acidosis, abnormal hepatic function tests, polyuria, renal failure
40
Cyclopentolate mechanismo of action and use in ophthalmology
Anticholinergic Mydriasis, cycloplegia
41
... is the technique of choice for cataract surgery and refers to the use of ultrasonic vibration of fragments of the lens with simultaneous irrigation and aspiration
Phacoemulsification
42
... is a technique where laser energy is used for corneal incision, capsulotomy, and fragmenting the lens. Supplemental oxygen is contraindicated during its use because of fire risk
Femtosecond laser
43
... refers to the removal of the lens, while leaving the posterior lens capsule and zonules intact to allow implantation of the intraocular lens
Extracapsular cataract extraction
44
... is the total removal of the opaque lens with the lens capsule, and it is rarely performed due to the large incision and a relatively high rate of complications
Intracapsular cataract extraction
45
... is a glaucoma surgery that creates a transscleral fistula to allow aqueous humor to drain into the subconjunctival space. ... is usually used to prevent scarring of the flap
Trabeculectomy Mitomycin C or 5-flurouracil (5-FU)
46
... devices are drainage implantable devices that shunt aqueous humor under the conjunctiva
Baerveldt and Ahmed
47
Minimally invasive glaucoma surgery (MIGS) includes procedures such as ...
CyPass, iStents, and trabectome.
48
... is a full-thickness corneal transplant.
Penetrating keratoplasty
49
... is a procedure used for the treatment of retinal detachment. A silicone band is placed around the globe within the extraocular muscles under the conjunctiva to push the sclera toward the detached retina. It can be used as the sole treatment or in combination with vitrectomy to treat retinal detachment
Scleral buckle
50
... is done for the treatment of choroidal melanoma. It is frequently combined with prophylactic vitrectomy with silicone oil injection to prevent retinal detachment from radiation. The duration of treatment is usually about one week
Radioactive plaque implantation
51
Eyelid procedures include the correction of ... (eyelid turning outward), ... (eyelid turning inward), ... (drooping of the upper eyelid), and ... (to remove redundant tissue of the eyelid)
ectropion entropion ptosis blepharoplasty
52
... refers to the surgical reopening of the obstructed channel between the lacrimal sac and the nasal cavity caused by a congenital defect or chronic infection
Dacryocystorhinostomy
53
Meaning of evisceration, enucleation, and exenteration in the context of ophthalmic surgery
Evisceration refers to the removal of the contents of the eye. Enucleation refers to removal of the eye itself including the globe, but leaving orbital contents such as bone, extraocular muscles, and fat in place. Exenteration refers to the removal of the entire contents of the orbit including the lacrimal gland, optic nerve, and orbital bones.
54
Comorbidities that Require Optimization Prior to Proceeding with Cataract Surgery
- Myocardial infarction, within 30 days for uncomplicated infarction and within 60 days for complicated infarction - Percutaneous coronary interventions, within 14 days without stents or 30 days with stents - Significant arrhythmias with hemodynamic compromise, e.g., ventricular tachycardia, atrial fibrillation with rapid ventricular rates - Decompensated heart failure - Acute serious pulmonary conditions, e.g., active pneumonia, upper respiratory infection with active symptoms, pulmonary embolus in past 3 months - Acute or recent severe neurologic conditions (e.g., altered mental status, stroke or transient ischemic attacks [TIA] within 3 months, uncontrolled epilepsy, increased intracranial pressure) - Malignant hypertension - Diabetic ketoacidosis or hyperosmolar hyperglycemic nonketotic syndrome
55
Some patients presenting for cataract surgery may have significantly elevated blood pressure or hyperglycemia on the day of surgery, but there is little evidence that these conditions increase adverse events warranting delay of surgery. T or F
T
56
About ophthalmic surgery, serious hemorrhagic complications are most probable in ... ; of intermediate probability in ... surgery; and least likely in ...
orbital and oculoplastic surgery vitreoretinal, glaucoma, and corneal transplant cataract surgery
57
Potential bleeding complications include ... ; however, the incidence of these events is low and estimated to be less than ...%
intraretinal hemorrhage, choroidal hemorrhage, vitreous hemorrhage, hyphema, and retrobulbar hemorrhage 0.4
58
It is safe to proceed with cataract surgery without stopping antiplatelet or warfarin therapy independently of international normalized ratio levels T or F
F It is safe to proceed with cataract surgery without stopping antiplatelet or warfarin therapy provided that the international normalized ratio level is within the therapeutic range
59
How to manage anticoagulation for a intermediate bleeding risk surgery?
For intermediaterisk surgery such as glaucoma surgery, warfarin and antiplatelet drugs may increase the risk of ntraoperative or postoperative bleeding. Survey studies show that 30%–80% of glaucoma surgeons discontinue anticoagulants 4–7 days prior to surgery and restart it the day after surgery, but other surgeons do not stop anticoagulants at all. If an interruption of anticoagulation treatment is needed, an individualized approach is recommended to minimize the risk of perioperative bleedin
60
Ocular blocks association with severe hemorrhagic complications
Ocular blocks are rarely associated with severe hemorrhagic complications
61
... nerve block may be required to obtain akinesia of the orbicularis oculi muscle of the lid, as its motor innervation is located outside the cone
Facial
62
... block had long been considered the gold standard of regional techniques for ophthalmic surgery until the 1990s with the introduction of ... block and ... block.
Retrobulbar peribulbar sub-Tenon
63
How to perform a retrobulbar block?
Retrobulbar block is achieved by injecting local anesthetic inside the muscular cone. With the globe in primary gaze, a 3-cm, 23- to 27-gauge needle with its bevel opening faced toward the globe is placed at the junction of the inferior and lateral walls of the orbit just above the inferior orbital rim. The needle is advanced parallel to the orbit floor (with a 10-degree elevation from the transverse plane) for approximately 15mm until it is past the equator of the eye. The needle is turned medially and slightly upward to aim toward an imaginary point behind the globe on the axis formed by the pupil and the macula where 2 to 5mL of local anesthetic solution is injected. The needle tip approaches but does not pass the midsagittal plane of the globe
64
After a retrobulbar block, some intorsion on downgaze is expected because ...
the superior oblique muscle is outside the muscle cone and may not be blocked.
65
Many modifications to the classical retrobulbar anesthetic injection have been described to minimize complications of the block. Blunt-tipped needles are advocated because they protect against ocular trauma and because they allowed more accurate definition of tissue planes. T or F
F Many modifications to the classical retrobulbar anesthetic injection have been described to minimize complications of the block. Traditionally, blunt-tipped needles were advocated because they were thought to protect against ocular trauma and because they allowed more accurate definition of tissue planes. However, studies have shown that blunt needles are as likely as sharp needles to cause globe penetration and optic nerve injury. Fine cutting needles produce minimal tissue distortion with little pain.
66
Compared with peribulbar block, retrobulbar block has a ... [quicker / slower] onset and is associated with ... [less / more] chemosis.
quicker less
67
Complciations of a retrobulbar block
1) Retrobulbar hemorrhage complicates about 1% of retrobulbar injections: - Venous hemorrhage spreads slowly and does not usually result in long-term visual problems; - Arterial hemorrhage can produce rapid orbital swelling, marked proptosis with immobility of the globe, inability to close the lids, and massive blood staining of the lids and conjunctiva. Compressive hematoma can threaten retinal perfusion, leading to severe visual loss. 2) Intravascular injection can occur despite a negative aspiration test. - The total dose of local anesthetic used is small, and systemic effects are unlikely, even if the total dose is given intravenously. - Accidental intra-arterial injection can cause central nervous system excitation and seizures. This occurs because of retrograde passage of local anesthetic solution from the ophthalmic artery to the internal carotid artery and delivery to the thalamus and other midbrain structures. 3) Injection of local anesthetic or retrograde tracking of local anesthetic along the optic nerve sheath into the subdural or subarachnoid space causes partial or total progressive brainstem anesthesia. Wideranging symptoms occur, from aphasia, confusion, and dysphagia to apnea, cardiac arrest, loss of consciousness, and seizures. 4) Optic nerve damage 5) Globe perforation with retinal detachment and vitreous hemorrhage
68
Optic nerve damage, or globe perforation with retinal detachment and vitreous hemorrhage, are devastating complications of retrobulbar block. Risk factors include ... This complication is associated with a poor prognosis, particularly in cases of delayed diagnosis
physician inexperience and a highly myopic eye (axial length longer than 25mm).
69
Describe the peribulbar block
For this block, the needle is introduced outside the cone, thus preventing retrobulbar hemorrhage and reducing the risk of optic nerve injury. The classic technique involves two injections: one inferiorly and temporally and the second superiorly and nasally. Peribulbar anesthesia may also be administered with one injection; a 3-cm, 23-gauge Atkinson needle is placed at the junction of the middle and lateral thirds of the lower lid just above the inferior orbital rim. The needle should be directed vertically backwards, parallel to the floor of the orbit. The needle insertion depth should be less than 25 mm. If contact is made with bone, the needle should be redirected slightly upward; then 5 to 10 mL of local anesthetic is injected. Studies support the use of peribulbar block in providing equivalent patient analgesia and operating conditions as retrobulbar block for a variety of ophthalmic procedures
70
Describe the eye sub-Tenon block
To avoid the complications associated with the use of sharp needles, a technique was developed using a blunt cannula under the fascia of Tenon. Various lengths of cannulas have been used. Using topical anesthesia with sedation, a speculum is placed to retract the lids. A 2- to 3-mm spot of cautery can be made 5mm from the limbus in the inferonasal or inferolateral quadrant. A 2-mm incision is made in the conjunctiva with blunt dissection through the fascia. A blunt cannula is directed posteriorly, but not beyond the equator of the globe, with injection of 1 to 3mL of local anesthetic. A small degree of conjunctival edema is often seen. Analgesia is usually excellent.
71
Describe the modified van Lint block
The needle is placed 1cm lateral to the orbital rim, and 2 to 4mL of anesthetic is injected deep on the periosteum just lateral to the superolateral and inferolateral orbital rim. The disadvantages of this block include discomfort, proximity to the eye, and postoperative ecchymoses
72
How to perform a facial block to prevent squeezing of the eyelids?
Akinesia of the orbicularis muscle, which is supplied by the facial nerve, can be achieved by blocking the nerve at its terminal branches (modified van Lint block), superior branches (Atkinson block), or proximal trunk (O’Brien or Nadbath block).
73
Describe the Atkinson block
The needle is inserted at the inferior margin of the zygomatic bone below the lateral margin of the orbit and 3 to 4mL of anesthetic solution is injected as the needle is advanced upward and temporally across the bone at 30 degrees from the vertical.
74
Describe the Nadbath–Rehman block
A 12-mm, 25-gauge needle is inserted perpendicular to the skin between the mastoid process and the posterior border of the mandible. The needle is advanced its full length, and after careful aspiration, 3mL of anesthetic is injected as the needle is withdrawn. This blocks the entire trunk of the facial nerve. The patient should be told to expect a lower facial droop for several hours postoperatively. The major disadvantage to this block is the proximity of the injection to important structures, such as the carotid artery and the glossopharyngeal nerve.
75
Local anesthetic solutions for regional anesthesia of the eye
For local anesthesia, a 1:1 ratio of bupivacaine 0.75% and lidocaine 2% without epinephrine is administered. Hyaluronidase is added to speed tissue penetration. Hyaluronidase can also be important in preventing anesthetic-related damage to the extraocular muscles. A human recombinant brand of hyaluronidase (Hylenex) is commercially available.
76
Advantages of regional block and MAC for eye surgery in comparison with general anesthesia
MAC with regional anesthesia provides many advantages over general anesthesia in lowering postoperative morbidity, mortality, and pulmonary omplications. There is better postoperative pain control, a lower incidence of intraoperative hypotension, faster postoperative recovery, less PONV, and fewer unplanned hospital admissions
77
Describe the Observer’s Assessment of Alertness/Sedation Scale
5: Responds to name spoken in normal tone / Normal speech / Normal Facial Expression / Clear eyes 4: Lethargic response to name spoken in normal tone / Mild slowing or thickening of Speech / Mild relaxation on Facial Expression / Glazed mild ptosis 3: Responds only after name spoken loudly or repeatedly / Slurring or slowing sppeech / Marked relaxation on Facial Expression / Glazed marked ptosis 2: Responds after mild prodding or shaking / Few recognized words 1: Does not respond to mild prodding or
78
An orbital block provides analgesia for ..., which will be sufficient for the duration of most ophthalmic procedures. For more complex procedures such as ..., the analgesic effect of a retrobulbar block may not be adequate to block all sensation. The addition of intravenous sedation with propofol and narcotics is sufficient for most patients. Low-dose ... can be added to the sedation regimen in patients who continue to experience discomfort.
2 to 3 hours enucleation, dacryocystorhinostomy, orbital decompression, scleral buckle, and radioactive plaque implantation ketamine and dexmedetomidine
79
Intranasal dexmedetomidine is well absorbed without the initial profound bradycardia associated with intravenous administration. When given as an adjunct agent, the dose should be reduced: ..., administered intranasally as a drop from a TB syringe. The elimination half-life of dexmedetomidine is about ... and even longer in elderly patients. Giving a single bolus toward the beginning of the procedure allows the drug to be eliminated during surgery and prevents adverse effects in the postanesthesia care unit (PACU)
0.5 to 0.7 mcg/kg 2 to 3 hours
80
The laryngeal mask airway (LMA) is widely used in both adult and pediatric patients undergoing ophthalmic procedures that do not require paralysis or airway protection from aspiration. Those procedures include ... in adults.
strabismus repair, scleral buckle, orbitotomy, enucleation, glaucoma, and cataract surgery
81
The prevention of coughing and bucking during emergence is another important goal in ophthalmic surgery because they both dramatically increase ... and the incidence of ...
IOP hemorrhage in both intraocular and extraocular surgery
81
Endotracheal intubation is required for selected ophthalmic procedures, including ... . Prevention of patient movement is critical during ... . In addition to ensuring an adequate depth of anesthesia, profound muscle relaxation must be ensured by using a nerve stimulator where 0/4 twitches and minimal posttetanic count are present while the diseased cornea has been removed and the eye is completely open. Movement at this time could result in ...
penetrating keratoplasty, deep anterior lamellar keratoplasty, combined corneal transplantation and vitrectomy, and some vitreoretinal procedures requiring muscle relaxation penetrating keratoplasty loss of ocular contents or choroidal hemorrhage
82
Nitrous oxide, if used as part of the anesthetic management, should be discontinued 15 to 20 minutes prior to the injection of ... used for retinal tamponade
sulfur hexafluoride (SF6), or octafluoropropane (C3F8)
83
About ... % of primary congenital glaucoma is inherited. Secondary glaucoma can be the result of a systemic condition such as ... . However, most cases of pediatric glaucoma have no identifiable cause.
10 neurofibromatosis, rubella, or Sturge–Weber syndrome (congenital capillary hemangiomatosis)
84
Strabismus surgery is the most common type of ophthalmic surgery performed in children. It has historically been associated with an incidence of postoperative vomiting (POV) of over ... % in numerous studies. Eberhart et al. identified strabismus surgery as an independent predictor for POV in children. Additional independent predictors include ... . When two, three, or four risk factors are present, the risk of POV is ...%, ...%, and ...%, respectively.
50 age over 3 years, duration of surgery greater than 30 minutes, and a history of POV or PONV in the patient, sibling, or parent 30 55 70
85
For children at high risk for POV (>... risk factors), as those having strabismus surgery are, a combination of ... should be administered prophylactically
2 a 5-HT3 antagonist and a steroid
86
Explain the oculorespiratory reflex (ORR)
the oculorespiratory reflex (ORR) leads to bradypnea and respiratory pauses. The afferent limb is the same as for the OCR; the efferent limb has not been clearly established. It is not responsive to anticholinergics. The ORR may be less appreciated because of the use of assisted modes of ventilation commonly used during strabismus surgery. Airway management is typically with an LMA unless a contraindication is present.
87
... are major risk factors for the development of retinopathy of prematurity (ROP). Other factors such as ... are also important predictors. Screening guidelines for ROP include a dilated fundus examination for all premature infants less than ... weeks’ gestational age or ... g at birth.
Gestational age and low birth weight anemia, sepsis, and bronchopulmonary dysplasia (BPD) 30 1500
88
can succynlcholine be used for induction of a patient with a open eye?
Succinylcholine, used as part of a rapid-sequence induction of anesthesia to permit rapid intubation and airway protection, causes a modest increase in IOP of 8 to 10mm Hg. There has been long-standing controversy surrounding the use of succinylcholine based primarily on anecdotal reports of vitreous loss during open eye surgery. There have been a number of studies where no extrusion of ocular contents has occurred following succinylcholine use. There are also no claims for such injury since 2000 in the ASA Closed Claims Project that is designed to detect patterns of injury during anesthesia. It should be stressed that during induction of anesthesia, there are many factors that may increase IOP such as crying, coughing, bucking, or straining, particularly during suboptimal intubating conditions. All these events increase IOP significantly more than succinylcholine. Based on the current evidence, succinylcholine may be used to facilitate endotracheal intubation in open eye injuries, despite its effect on IOP.
89
IOP can increase by an average of ... mm Hg higher than pre-anesthesia induction values when a patient is placed in steep Trendelenburg position, and remains significantly elevated while the patient remains in this position ... has been shown to be effective in lowering IOP and its use has been shown to attenuate the increase in IOP during laparoscopic surgery in steep Trendelenburg position without decreasing ocular perfusion pressure.
13 Dexmedetomidine
90
In an ASA closed claims analysis of eye injuries during ophthalmic surgery associated with anesthesia in 1992, Gild et al. found that ... was the most common single mechanism of injury
patient movement such as bucking or coughing
91
The primary etiologies of perioperative visual loss (POVL) include
1) Occlusion of the retinal vessels can result in interruption of the arterial supply: This process occurs most commonly from increased intraocular pressure (IOP) resulting from external pressure during surgical positioning. Other causes of increased IOP include processes within the globe such as vitreous hemorrhage and thrombotic or embolic processes that may result in occlusive disease of the retinal vasculature. 2) Ischemic optic neuropathy (ION): ION is the most frequently reported condition associated with permanent POVL. ION is caused by any process that leads to inadequate delivery of oxygen to the optic nerves, including low mean arterial pressure (MAP), cardiac and spine surgeries, prone positioning, vasculature vasoconstriction due to hypocarbia, or factors affecting oxygen delivery such as decreased cardiac output, worsening anemia, or hypoxia. 3) Cortical blindness: Cortical blindness results from a stroke in the parietooccipital areas of the cortex responsible for reception and integration of visual input. Etiologies include hypoxic and/or ischemic events such as hypoperfusion injuries as well as thrombotic and embolic events. Shen et al. reported that patients younger than 18 years undergoing spine surgery had the greatest risk of developing POVL and cortical blindness, in particular 4) Central retinal artery occlusion (CRAO): Central retinal artery occlusion is an ocular emergency and is the equivalent of a cerebral stroke. Patients typically present with profound, acute, painless monocular visual loss. Patients with CRAO usually present with sudden and profound unilateral loss of vision. More than 90% of CRAOs are non-arteritic in origin. Ipsilateral carotid artery atherosclerosis or branch retinal artery occlusion are the most common causes of CRAO. Other causes of CRAO include cardiogenic embolism, hematologic hypercoagulable states, and vascular diseases
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Describe the different types of Ischemic optic neuropathy (ION)
There are two types of ION. Anterior ION (AION) is caused by acute disruption of the blood supply to the posterior ciliary body and characterized by swelling of the optic nerve head. Posterior ION (PION) occurs when there is ischemia due to compromise of blood supply to watershed areas in the posterior aspect of the optic nerve. Clinical findings include unilateral or bilateral visual acuity or visual field changes, an afferent pupillary defect, and an abnormal-appearing optic nerve when the ION is anterior
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The blood supply to the optic nerve is tenuous and damage can be caused by impaired autoregulation in the presence of any stress factor leading to capillary filling pressure falling below a critical level. The associated risk factors include ... Surgery-related conditions include the ...
systemic hypertension, diabetes mellitus, hyperlipidemia, hypercoagulable disorders, sleep apnea, anemia, smoking, age over 50 years, peripheral vascular disease, coronary artery disease, and obesity prone position, prolonged surgical duration, substantial blood loss, and prolonged use of intraoperative vasoactive agents in high-risk patients.