biologic use

Question 1

Atopic derm tx

Answer 1

1. topical CS or calcinuerin inhibitor
2. sys: oral immunosupp, JAK, biologic
   3.Flares: mid pot TCS
3. Refractory: oral IS, consider biologic
   5.mx: low pot TCS

Question 2

Mild-mod psoriasis

Answer 2

-topical TCS, calcineurin +/- sys agent

Question 3

Mod-severe psoriasis

Answer 3

1. MTX +/- topical
   -biologic last line (TNF, CTLA-4, IL-17, IL-12/23)

Question 4

Severe psoriasis

Answer 4

1. biologic (TNF, CTLA-4, IL-17, IL-12/23)
2. retinoid, cyclo, MTX

Question 5

RA tx

Answer 5

1. MTX (lef or sulf if CI) +/- topical
   -add TNF, abatacept, IL-6 or JAK

Question 6

Lupus tx

Answer 6

1. hydroxychloroquine
2. NSAIDs
3. GC
4. MTX, myco, cyclop, AZA
5. biologics: belimumab, anifrolumab, rituximab

Question 7

Cutaneous lupus

Answer 7

-TCS or TCI
-PO GC, MTX, myco

Question 8

Lupus nephritis

Answer 8

mild-mod: GC+/- IS

severe: myco/cyclo +/- GC + belimumab
-or CI + myco + GC