What do lipids include?
triglycerides and phospholipids
What two molecules do lipids consist of?
glycerol and fatty acids
Are lipids insoluble?
Yes but they can dissolve in organic liquids e.g. ethanol
What is different about a lipid from a carbohydrate?
contains proportionally less oxygen than carbohydrates.
What does a glycerol look like?
has 3 carbons, 5 hydrogens and 3 OH groups
https://www.differencebetween.com/difference-between-glycerol-and-vs-fatty-acids/
What is the general formula of fatty acids? And give an example of what they could look like.
COOH.(CH2)nCH3
https://www.creative-proteomics.com/blog/index.php/biref-introduction-of-short-chain-fatty-acids/
Give the definition of a glycerol
It is an alcohol that dissolves in water meaning it is a hydrophilic molecule
Why are triglycerides not considered polymers?
made up of two diff. types of subunits ( glycerol and fatty acids) which have different structures.
Triglycerides aren’t made up of identical monomers.
Are fatty acids hydrophobic or hydrophilic?
Hydrophobic meaning they are repelled by water.
What does a triglyceride look like?
https://clinidiabet.com/en/infodiabetes/cardiodiabetes/15.htm
How does one fatty acid differ from another?
By length of hydrocarbon chain (CH2n)
variation of lipid structure caused by diff. types of fatty acid
What are the 2 types of fatty acid?
saturated and unsaturated
What does the hydrocarbon chain in a saturated fatty acid consist of?
no carbon-to-carbon double bonds
is a straight solid hydrocarbon chain
has the maximum no. of hydrogen atoms bonded to the carbon atoms, hence the term saturated.
What is does a unsaturated fatty acid hydrocarbon chain consist of?
one or many (mono/poly) carbon-to-carbon double bonds
chain is kinked where there is a double C bond so is more of a fluid/liquid
doesn’t contain max. no. of H atoms since C has used one of its bonds to double bond with another C, hence the term unsaturated
How is a triglyceride formed and broken? (6 points)
one glycerol molecule combines with three fatty acid molecules
there is an ester bond between the fatty acid and glycerol
one triglyceride will therefore have 3 ester bonds
ester bonds are formed by condensation reactions
water formed from the H in the OH group on glycerol and full OH group from COOH unit from the fatty acid
if a lipid is broken down, it undergoes a hydrolysis reaction.
Which type of fat can damage the heart and coronary arteries and contribute to heart disease?
saturated fat
What is a low-density lipoprotein? (LDL)
contain and transport saturated fat causing harm
this fatty material can block major arteries (plaque), and can cause myocardial infarction (heart attack)
What is a high density lipoprotein (HDL)?
contain and transport unsaturated fats carrying harmful fats away to the liver for disposal
high proportion of HDL in blood lowers risk of heart disease
What health implications that high fat intake cause?
atherosclerosis, aneurysm, and myocardial infarction
What does an aneurysm do?
damages the thin artery wall by inflation. the artery can’t handle the pressure and blood cant get away from the heart
what are the properties of lipids?
insoluble in water but soluble in organic solvents
fats are solid at room temp.
oils are liquid at room temp.
Give the 6 functions of lipids and describe each of them.
Energy storage - in seeds and animals, release more energy than carbohydrates when used as an alternative respiratory substrate
Protection of vital organs - used as shock absorption, preventing physical damage to internal organs
Thermal insulation - used as heat insulator e.g blubber in whales, seals and polar bears
Buoyancy - lipids are less dense than water so they float, they have a role in maintaining buoyancy in organisms such as fish
Metabolic water - produced when lipids are oxidised by respiration, vital in desert animals such as camels whose hump is made of fat.
Waterproofing - waxes are hydrophobic and cover the exoskeleton of insects and cuticles of plant leaves, reducing water loss
What are phospholipids made of?
they have glycerol, two fatty acids and a phosphate group
Which part of the phospholipid is hydrophilic? And which is hydrophobic?
The phospholipid head - including glycerol and phosphate group.
Fatty acid tails